Figure 9.

Changes in expression of direct p53 target genes induced by Ad5 infection. The 50 or so genes that are direct p53 targets in human lung fibroblasts [94] are shown clustered based on the changes in their expression observed in adenovirus type 5 (Ad5) infected human foreskin fibroblasts. The column labeled p53 summarizes the p53 induced alterations in expression of these genes, which are listed at the right. Ramps above panels indicate increases in time after infection.