Table 1

Cellular functions associated with genes significantly regulated by Ad5 infection

GO term ID

GO term description

P value

Cellular functions associated with down-regulated genes

GO:0045449

Regulation of transcription

5.97 × e^-06

GO:0007154

Cell communication

1.63 × e^-04

GO:0007165

Signal transduction

1.05 × e^-03

GO:0007275

Development

5.42 × e^-03

Cellular functions associated with up-regulated genes

GO:0006281

DNA repair

< 0.00 × e^-11

GO:0042254

Ribosome biogenesis and assembly

< 0.00 × e^-11

GO:0007046

Ribosome biogenesis

3.60 × e^-09

GO:0008380

RNA splicing

4.73 × e^-09

GO:0006260

DNA replication

1.71 × e^-08

GO:0007049

Cell cycle

2.03 × e^-08

GO:0000279

M phase

3.52 × e^-08

GO:0006913

Nucleocytoplasmic transport

1.12 × e^-05

GO:0006270

DNA replication initiation

4.37 × e^-05

GO:0006334

Nucleosome assembly

8.81 × e^-05

GO:0051169

Nuclear transport

1.86 × e^-04

GO:0051301

Cell division

1.95 × e^-04

GO:0031497

Chromatin assembly

7.92 × e^-04

GO:0009156

Ribonucleoside monophosphate biosynthesis

4.32 × e^-03

GO:0009124

Nucleoside monophosphate biosynthesis

7.06 × e^-03

Ad5, adenovirus type 5; GO, Gene Ontology.

Miller et al. Genome Biology 2007 8:R58   doi:10.1186/gb-2007-8-4-r58