Genome Biology

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The innate immune repertoire in Cnidaria - ancestral complexity and stochastic gene loss

David J Miller, Georg Hemmrich, Eldon E Ball, David C Hayward, Konstantin Khalturin, Noriko Funayama, Kiyokazu Agata and Thomas CG Bosch*

Genome Biology 2007, 8:R59 doi:10.1186/gb-2007-8-4-r59

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Research article   Open Access

High amino acid diversity and positive selection at a putative coral immunity gene (tachylectin-2)

Marshall L Hayes, Ron I Eytan, Michael E Hellberg BMC Evolutionary Biology 2010, 10:150 (19 May 2010)

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The gene complement of the ancestral bilaterian - was Urbilateria a monster?

David J Miller, Eldon E Ball Journal of Biology 2009, 8:89 (19 November 2009)

Bilateral animals have selectively shed genes as they evolved from their hypothetical ancestor, Urbilateria. Miller and Ball review this genomic history and ask if a recent paper in BMC Evolutionary Biology points to an ancestral worm.

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Molecular architecture of the fruit fly's airway epithelial immune system

Christina Wagner, Kerstin Isermann, Heinz Fehrenbach, Thomas Roeder BMC Genomics 2008, 9:446 (29 September 2008)

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Novel genes dramatically alter regulatory network topology in amphioxus

Qing Zhang, Christian M Zmasek, Larry J Dishaw, M Gail Mueller, Yuzhen Ye, Gary W Litman, Adam Godzik Genome Biology 2008, 9:R123 (4 August 2008)

Domain rearrangements in the innate immune network of amphioxus suggests that domain shuffling has shaped the evolution of immune systems.

Research   Open Access

Comparative analysis of septic injury-inducible genes in phylogenetically distant model organisms of regeneration and stem cell research, the planarian Schmidtea mediterranea and the cnidarian Hydra vulgaris

Boran Altincicek, Andreas Vilcinskas Frontiers in Zoology 2008, 5:6 (27 April 2008)

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Coral life history and symbiosis: Functional genomic resources for two reef building Caribbean corals, Acropora palmata and Montastraea faveolata

Jodi A Schwarz, Peter B Brokstein, Christian Voolstra, Astrid Y Terry, David J Miller, Alina M Szmant, Mary Coffroth, Mónica Medina BMC Genomics 2008, 9:97 (25 February 2008)

Research   Open Access

Conservation and divergence of gene families encoding components of innate immune response systems in zebrafish

Cornelia Stein, Mario Caccamo, Gavin Laird, Maria Leptin Genome Biology 2007, 8:R251 (27 November 2007)

Analysis of several fish genomes reveals components of the innate immune system and identifies orthologous relationships between gene families of fish and mammals.

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Surprising complexity of the ancestral apoptosis network

Christian M Zmasek, Qing Zhang, Yuzhen Ye, Adam Godzik Genome Biology 2007, 8:R226 (24 October 2007)

A comparative genomics approach revealed that the genes for several components of the apoptosis network with single copies in vertebrates have multiple paralogs in cnidarian-bilaterian ancestors, suggesting a complex evolutionary history for this network.