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Functional dissection of the ash2 and ash1 transcriptomes provides insights into the transcriptional basis of wing phenotypes and reveals conserved protein interactions

Sergi Beltran* email, Mireia Angulo* email, Miguel Pignatelli email, Florenci Serras email and Montserrat Corominas email

Departament de Genètica, Universitat de Barcelona, Diagonal 645, 08028 Barcelona, Spain

author email corresponding author email* Contributed equally

Genome Biology 2007, 8:R67doi:10.1186/gb-2007-8-4-r67

Published: 28 April 2007

Subject areas: Development, Genetics, Genome studies


Additional files

Additional data file 1:

Unique genes up- and downregulated over 1.5-fold (log2 ratio = 0.58) or 2.0-fold (log2 ratio = 1) in each mutant allele

Format: PDF Size: 8KB Download file

This file can be viewed with: Adobe Acrobat Reader

Additional data file 2:

Genes downregulated and upregulated over 1.5- and 2.0-fold in ash2I1

Format: XLS Size: 158KB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional data file 3:

Genes downregulated and upregulated over 1.5- and 2.0-fold in ash2112411

Format: XLS Size: 252KB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional data file 4:

Genes downregulated and upregulated over 1.5- and 2.0-fold in ash122

Format: XLS Size: 61KB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional data file 5:

GO annotations of the genes downregulated over 1.5-fold in ash2I1

Format: HTML Size: 3.1MB Download file

Additional data file 6:

GO annotations of the genes upregulated over 1.5-fold in ash2I1

Format: HTML Size: 2MB Download file

Additional data file 7:

GO annotations of the genes downregulated over 2.0-fold in ash2I1

Format: HTML Size: 1.3MB Download file

Additional data file 8:

GO annotations of the genes upregulated over 2.0-fold in ash2I1

Format: HTML Size: 983KB Download file

Additional data file 9:

GO annotations of the genes downregulated over 1.5-fold in ash2112411

Format: HTML Size: 5MB Download file

Additional data file 10:

GO annotations of the genes upregulated over 1.5-fold in ash2112411

Format: HTML Size: 2.8MB Download file

Additional data file 11:

GO annotations of the genes downregulated over 2.0-fold in ash2112411

Format: HTML Size: 1.4MB Download file

Additional data file 12:

GO annotations of the genes upregulated over 2.0-fold in ash2112411

Format: HTML Size: 1.2MB Download file

Additional data file 13:

GO annotations of the genes downregulated over 1.5-fold in ash122

Format: HTML Size: 912KB Download file

Additional data file 14:

GO annotations of the genes upregulated over 1.5-fold in ash122

Format: HTML Size: 1MB Download file

Additional data file 15:

GO annotations of the genes downregulated over 2.0-fold in ash122

Format: HTML Size: 305KB Download file

Additional data file 16:

GO annotations of the genes upregulated over 2.0-fold in ash122

Format: HTML Size: 469KB Download file

Additional data file 17:

GO annotations of wing disc genes identified by Klebes et al. [37]

Format: HTML Size: 677KB Download file

Additional data file 18:

Genes misregulated in ash2 and ash1 mutants preferentially expressed in the wing disc and in the prospective wing-hinge or body wall region

Format: PDF Size: 11KB Download file

This file can be viewed with: Adobe Acrobat Reader

Additional data file 19:

GO annotations of the genes upregulated in Sin3A deficient cells according to Pile et al. [49]

Format: HTML Size: 1.8MB Download file

Additional data file 20:

Genes misregulated in Sin3A deficient cells that are also misexpressed in ash2 and/or ash1 mutants

Format: PDF Size: 11KB Download file

This file can be viewed with: Adobe Acrobat Reader

Additional data file 21:

FDR adjusted p values for the GO terms displayed in Figure 2a

Format: PDF Size: 16KB Download file

This file can be viewed with: Adobe Acrobat Reader

Additional data file 22:

Distribution of regulated genes in Molecular function GO classes

Format: TIFF Size: 707KB Download file

Additional data file 23:

Distribution of regulated genes in Biological process GO classes

Format: TIFF Size: 677KB Download file

Additional data file 24:

ASH2, HCF and Sin3A are found in the nucleus

Format: TIFF Size: 828KB Download file


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