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Open Access Research

Evolution of the core and pan-genome of Streptococcus: positive selection, recombination, and genome composition

Tristan Lefébure and Michael J Stanhope*

Author Affiliations

Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA

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Genome Biology 2007, 8:R71  doi:10.1186/gb-2007-8-5-r71

Published: 2 May 2007

Additional files

Additional data file 1:

Gene content table describing the presence and absence of gene clusters per genome

Format: XLS Size: 1.3MB Download file

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Open Data

Additional data file 2:

Composition of the clusters, with links to GenBank protein accession numbers

Format: CSV Size: 622KB Download file

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Additional data file 3:

Results are presented for equal weights as well as following a model that penalized gene gain with respect to gene loss

Format: XLS Size: 272KB Download file

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Open Data

Additional data file 4:

Genes showing evidence of recombination and positive selection

Format: XLS Size: 123KB Download file

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Open Data

Additional data file 5:

Genes and lineages under positive selection for the four analyzed core-genomes, with gene annotation from NCBI and TIGR

Format: XLS Size: 154KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data