|
Genes related to oligodendrocyte differentiation are differentially expressed in Nfia-/- mice at P16 |
||
| Gene name |
Fold change of mRNA expression in Nfia-/- versus Nfia+/+ micea |
Reference |
|
|
||
| Genes typically expressed in oligodendrocyte precursors or related to de-differentiation of precursor cells |
||
| Hmgb2 |
1.92 |
[45] |
| Sox2 |
1.28 |
[46] |
| Sox4 |
1.33/1.44 |
[47] |
| Sox11 |
1.88/2.22 |
[47] |
| Tenascin-C |
1.47 |
[48] |
| Myef2b |
1.2 |
[39] |
| Genes typically expressed in mature oligodendrocytes or related to terminal oligodendrocyte differentiation |
||
| Mobp |
-2.11/-2.10/-1.99/-1.98 |
[49] |
| Mal |
-2.43 |
[50] |
| Mog |
-1.95 |
[51] |
| Claudin 11 |
-1.67 |
[52] |
| Plp1 |
-1.58 |
[53] |
| Ugt8 |
-1.54/-1.45 |
[50] |
| Mag |
-1.52 |
[53] |
| Dio2c |
-1.43 |
[38] |
| Car2 |
-1.35 |
[54] |
|
aAccording to microarray analysis; for genes represented by more than one probe set, the individual fold changes for each probe set are given. bIndirect link to oligodendrocyte maturation (My-EF2 can repress expression of myelin basic protein). cIndirect link to oligodendrocyte maturation (Dio2 catalyzes thyroxine to tri-iodothyronine conversion, and tri-iodothyronine triggers terminal differentiation of oligodendrocytes). P16, postnatal day 16. | ||
Wong et al. Genome Biology 2007 8:R72 doi:10.1186/gb-2007-8-5-r72 |
||