Table 1

Tumor, treatment, and outcome characteristics of patients providing human SCC cell lines
Cell line
 Age (years at diagnosis)
 Sex
 Stage
 TNM
 Primary site
 Specimen site
 Prior therapy
 Status
 Survival (months)
UM-SCC 1
 72
 M
 I
 T1N0M0
 FOM
 Local recur
 R
 DWOD
 15
UM-SCC 5
 59
 M
 III
 T2N1M0
 Supraglottic larynx
 Pri bx
 S
 DOD
 8
UM-SCC 6
 37
 M
 II
 T2N0M0
 Tongue
 Pri bx
 N
 LTF
UM-SCC 9
 72
 F
 II
 T2N0M0
 Tonsil/BOT
 Local recur
 R
 DOD
 15
UM-SCC 11A
 65
 M
 V
 T2N2aM0
 Hypopharynx
 Pri bx
 N
 DOD
 14
UM-SCC 11B




Pri resect
 C

UM-SCC 22A
 59
 F
 III
 T2N1M0
 Hypopharynx
 Pri bx
 N
 DOD
 10
UM-SCC 22B




LN met
 N

UM-SCC 38
 60
 M
 IV
 T2N2aM0
 Tonsil/BOT
 Pri
 N
 DOD
 11
UM-SCC 46
 57
 F
 III
 No TMN Given
 Suprglottic larynx
 Local recur
 R, S
 DOD
 6

The clinical information was kindly provided by Drs Thomas E Carey and Carol R Bradford, and some information was previously presented in the literature. 'Primary sites' refers to the origin of the primary tumor. 'Specimen site' refers to origin of tissue used to establish cultures. 'Prior therapy' refers to therapy given before the specimen used for culture was obtained. 'Survival' represents time in months from diagnosis to last follow up. BOT, base of tongue; bx, biopsy; C, chemotherapy; DOD, died with disease; DWOD, died without disease; F, female; FOM, floor of mouth; LN, lymph nodes; LTF, lost to follow-up; M, male; met, metastasis; N, none; NED, no evidence of disease; Pri, primary tumor site; R, radiation; recur, recurrence; resect, surgical resection specimen; SCC, squamous cell carcinoma; S, surgery; TNM, tumor-node-metastasis (staging system); UM-SCC, University of Michigan series head and neck squamous cell carcinoma.

Yan et al. Genome Biology 2007 8:R78   doi:10.1186/gb-2007-8-5-r78

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