Table 1 |
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Conservation in the 5 kilobases upstream sequences in all protein coding and intergenic miRNA genes |
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| Human versus |
Protein coding genes |
Intergenic miRNA genes |
Relative conservation |
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|
|
|
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| Number of orthologous |
Block coverage |
Average block identity |
Number of orthologous |
Block coverage |
Average block identity |
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|
|
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| Chimp |
23,643 |
93.03% |
98.15% |
144 |
93.46% |
98.51% |
0.46% |
| Mouse* |
22,790 |
23.30%* |
73.53% |
142 |
36.17%* |
74.72% |
55.24% |
| Rat* |
22,161 |
22.46%* |
73.49% |
140 |
34.95%* |
74.68% |
55.61% |
| Dog* |
23,276 |
44.36%* |
75.58% |
145 |
61.72%* |
76.96% |
39.13% |
| Opossum* |
17,334 |
7.28%* |
74.90% |
104 |
11.65%* |
76.08% |
60.03% |
| Chicken |
8,087 |
4.55% |
74.87% |
54 |
6.08% |
76.80% |
33.63% |
| Fugu |
6,257 |
4.13% |
72.17% |
47 |
2.73% |
73.65% |
-33.90% |
| Tetraodon |
7,821 |
3.43% |
72.10% |
60 |
2.31% |
73.40% |
-32.65% |
|
|
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|
This table lists the number of genes orthologous to human genes in each of the genomes tested, the percentage of upstream sequence conservation (in >65% block identity), and the weighted average within block identity. Relative conservation (in terms of block coverage) is also listed for the microRNA (miRNA) versus protein coding genes. *Species for which the block coverage of miRNA gene upstream regions is statistically significantly higher than that of the promoters of the protein coding genes. |
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|
Mahony et al. Genome Biology 2007 8:R84 doi:10.1186/gb-2007-8-5-r84 |
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