Genome Biology

official impact factor 6.89

Open Access Highly Access Research

GSMN-TB: a web-based genome-scale network model of Mycobacterium tuberculosis metabolism

Dany JV Beste1, Tracy Hooper1, Graham Stewart1, Bhushan Bonde1, Claudio Avignone-Rossa1, Michael E Bushell1, Paul Wheeler2, Steffen Klamt3, Andrzej M Kierzek1 and Johnjoe McFadden1*

Author Affiliations

1 School of Biomedical and Molecular Sciences, University of Surrey, Stag Hill, Guildford, Surrey, GU2 7XH, UK

2 Tuberculosis Research Group, Veterinary Laboratories Agency (Weybridge), New Haw, Addlestone KT15 3NB, UK

3 Max Planck Institute for Dynamics of Complex Technical Systems, Sandtorstrasse, D-39106 Magdeburg, Germany

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Genome Biology 2007, 8:R89 doi:10.1186/gb-2007-8-5-r89

Published: 23 May 2007

Additional files

Additional data file 1:

Illustrated is the estimated macromolecular composition for M. tuberculosis.

Format: XLS Size: 99KB Download file

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Additional data file 2:

Shown are the calculations used to estimate the composition shown in Additional data file 1.

Format: XLS Size: 36KB Download file

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Additional data file 3:

Shown is the conversion between stoichiometric formulae and mmol/l per gram of biomass.

Format: XLS Size: 19KB Download file

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Additional data file 4:

Shown are the reaction formulae, limits, EC numbers, genes, and pathway classifications.

Format: XLS Size: 242KB Download file

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Additional data file 5:

Provided are references for the reactions shown in Additional data file 4.

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Additional data file 6:

Provided are metabolite names.

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Additional data file 7:

Provided are instructions on how to use the GSMN-TB server, illustrated by screenshots.

Format: PDF Size: 518KB Download file

This file can be viewed with: Adobe Acrobat Reader

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