Table 3 |
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|
Comparison of theoretical gene essentiality predictions with results of TraSH experiment in vitro |
|||
| TraSH threshold of 0.2 |
TraSH threshold of 0.1 |
TraSH threshold of 0.1, altered energetic parameters |
|
|
|
|||
| True positive |
154 |
115 |
114 |
| False positive |
71 |
110 |
110 |
| True negative |
385 |
432 |
432 |
| False negative |
95 |
48 |
49 |
| Sensitivity |
62% |
71% |
70% |
| Specificity |
84% |
80% |
80% |
| Correct predictions |
76% |
78% |
77% |
| Pa |
< 2.2 × 10-16 |
< 2.2 × 10-16 |
< 2.2 × 10-16 |
|
|
|||
|
aFisher exact test. TraSH, transposon site hybridization. |
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|
Beste et al. Genome Biology 2007 8:R89 doi:10.1186/gb-2007-8-5-r89 |
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