Genome Biology

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Large-scale analysis of transcriptional cis-regulatory modules reveals both common features and distinct subclasses

Long Li1, Qianqian Zhu1, Xin He3, Saurabh Sinha3 and Marc S Halfon1,2,4,5*

Author Affiliations

1 Department of Biochemistry, State University of New York at Buffalo, Buffalo, NY 14214, USA

2 Department of Biological Sciences, State University of New York at Buffalo, Buffalo, NY 14214, USA

3 Department of Computer Science, University of Illinois Urbana-Champaign, Urbana, IL 61801, USA

4 New York State Center of Excellence in Bioinformatics and the Life Sciences, Buffalo, NY 14203, USA

5 Department of Molecular and Cellular Biology, Roswell Park Cancer Institute, Buffalo, NY 14263, USA

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Genome Biology 2007, 8:R101 doi:10.1186/gb-2007-8-6-r101

Published: 5 June 2007

Additional files

Additional data file 1:

Figures S1-1 (basic properties of the CRMs), S1-2 (alternative mapping to tissues), S1-3 (distribution of intronic CRMs), and Table S1-1 (GO terms).

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Additional data file 2:

GFFv3 file giving the locations and additional information on the REDfly analysis CRMs.

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Additional data file 3:

Figures S3-1 through S3-4 and additional data.

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Additional data file 4:

Overlap of REDfly CRMs with ultra-conserved sequences.

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Additional data file 5:

Table S5-1 and Figure S5-1.

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Additional data file 6:

Differences between the original FTT and the revised FTT-Z (Figures S6-1 and S6-2) and CRM subsets with significant FTT-Z scores (Table S6-1).

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