Table 2

Representative sample of genes with the highest number of ORESTES

No. of ORESTES
Gene symbol
No. of UniGene ESTs
Full name (alias)

Ubiquitously expressed genes with a high number of UniGene ESTs



     142
RPS8
3,382
Ribosomal protein S8
     115
EEF1A1
29,374
Eukaryotic translation elongation factor 1 alpha 1
     77
HLA-B
4,536
Major histocompatibility complex, class I, B
     71
RPL3
11,561
Ribosomal protein L3
     62
NCL
2,970
Nucleolin
     55
RPL28
2,394
Ribosomal protein L28
     55
RPL7A
5,864
Ribosomal protein l7a
     51
RPSA
5,623
Ribosomal protein SA
     50
PABPC1
4,385
Poly(A) binding protein, cytoplasmic 1
     34
RPS18
2,292
Ribosomal protein S18




Known epidermis specific genes



     402
KRT1
134
Keratin 1
     217
DMKN
275
Dermokine
     140
LEP7
5
Late envelope protein 7 (xp32)
     100
FLG
5
Filaggrin
     71
KRT2A
12
Keratin 2A
     62
SPRR2E
36
Small proline-rich protein 2E
     61
CASP14
19
Caspase 14
     59
CDSN
91
Corneodesmosin
     56
hKPRP
7
Human keratinocyte proline rich protein
     54
PKP1
263
Plakophilin 1
     32
SBSN
49
Suprabasin
     30
DSG1
61
Desmoglein 1




Genes with unknown function



     193
TSPAN5
526
Tetraspanin 5
     127
DUOX2
64
Dual oxidase 2
     99
TMEM14C
476
Transmembrane protein 14C
     99
SERPINA12
11
Serpin peptidase inhibitor, clade A, member 12
     66
SLC22A5
142
Solute carrier family 22, member 5
     56
FLG2
10
Filaggrin 2 (ifapsoriasin)
     41
C7orf24
309
Chromosome 7 open reading frame 24

Toulza et al. Genome Biology 2007 8:R107   doi:10.1186/gb-2007-8-6-r107