  ResearchFunctional coordination of alternative splicing in the mammalian central nervous systemMatthew Fagnani* 1,2 1Banting and Best Department of Medical Research, Centre for Cellular and Biomolecular Research, University of Toronto, 160 College Street, Toronto, Ontario, Canada. M5S 3E1 2Department of Molecular and Medical Genetics, Centre for Cellular and Biomolecular Research, University of Toronto, 160 College Street, Toronto, Ontario, Canada. M5S 3E1 3Department of Electrical and Computer Engineering, University of Toronto, 40 St. George's Street, Toronto, Ontario, Canada 4School of Computer Science and Engineering, Hebrew University, Jerusalem 91904, Israel
Genome Biology 2007, 8:R108doi:10.1186/gb-2007-8-6-r108
Subject areas: Neurobiology, Molecular biology, Bioinformatics, Genome studies Additional filesAdditional data file 1: Provided is supplemental information on genes with microarray detected tissue specific AS levels, additional details on Materials and Methods, and additional Figures (1-5). Format: PDF Size: 2.2MB Download file This file can be viewed with: Adobe Acrobat Reader Additional data file 2: Provided is information on tissue specific AS events. Format: XLS Size: 48KB Download file This file can be viewed with: Microsoft Excel Viewer Additional data file 3: Provided is information on CNS regulated AS events. Format: XLS Size: 57KB Download file This file can be viewed with: Microsoft Excel Viewer Additional File 4: Provided is information on correlated pairs of AS events belonging to the same genes. Format: XLS Size: 587KB Download file This file can be viewed with: Microsoft Excel Viewer Additional data file 5: Summarized are motifs associated with CNS specific AS events detected from ab initio searches. Format: XLS Size: 585KB Download file This file can be viewed with: Microsoft Excel Viewer Additional data file 6: Summarized are experimentally defined sequences/motifs associated with neural specific AS used for searches Format: XLS Size: 36KB Download file This file can be viewed with: Microsoft Excel Viewer Additional data file 7: Summarized are experimentally defined motifs/subsequences significantly enriched in exons and introns associated with CNS regulated AS events identified in the AS microarray data. Format: XLS Size: 20KB Download file This file can be viewed with: Microsoft Excel Viewer Additional data file 8: Summarized are the number and statistical significance of ab initio motifs detected at each exonic and intronic location, and in each group. Format: XLS Size: 18KB Download file This file can be viewed with: Microsoft Excel Viewer Additional data file 9: Summarized are motifs associated with CNS specific AS events detected by searching with the Improbizer program. Format: PDF Size: 174KB Download file This file can be viewed with: Adobe Acrobat Reader Additional data file 10: Shown are conservation levels of motifs associated with CNS specific AS events detected from ab initio searches. Format: XLS Size: 14KB Download file This file can be viewed with: Microsoft Excel Viewer Additional data file 11: Provided are GenASAP values and C1-A-C2 exon sequences for 3,707 AS events profiled in 27 mouse tissues. Additional microarray data has been deposited in GEO under accession GSE8081. Format: XLS Size: 4.5MB Download file This file can be viewed with: Microsoft Excel Viewer |
|
|
|
 | Log on / register BioMed Central home | Journals A-Z | Feedback | Support | My details |
home | comment | reviews | reports | deposited research | refereed research | interactions | supplements | search | information | my journal |
 | .refereed research |
| |||||||||||
on Google Scholar
author email
corresponding author email|
|
| © 1999-2008 BioMed Central Ltd unless otherwise stated < info@genomebiology.com > Terms and conditions |