Table 4

Proteins identified within the soluble sub-proteome of O. anthropi containing predicted export signal peptides

Accesion no. (NCBI)

Function

Signal peptide


17982947

Methionyl-tRNA synthetase

MSPLTNFFS

    R
AYHA

17983887

Dihydroxy-acid dehydratase

M

    K
MPPY
    R
S
    R
TTTHG
    R
NMAGA

17982453*

Hypothetical protein (immunoreactive 28 kDa omp)

MNT

    R
ASNFLAASFSTIMLVGAFSLPAFA

17983949

3-Deoxy-manno-oculosonate cytidylyltransferase

MVLLPPRKTARVGT

    RRK
PVFLSQTCANG

17984491*

Lipoprotein (ABC transporter substrate binding protein)

MSSVLS

    R
YALT
    RR
AGL
    K
ALLFTAAALTVGFASAPSHA

27353255

Transriptional regulatory protein

M

    R
AFT
    R
FSYSHS

17982679

Protein translation elongation factor Tu

MCW

    R
LSGS
    R
T
    KR
TTAMA

17982015*

Malate dehydrogenase

M

    RK
ETIMA
    R
N
    K
IALIGSGMIGGTLA

17982340*

Periplasmic dipeptide transport protein precursor

MGCARQAFPW

    RR
TIM
    K
FYQ
    K
LLAATALVALMSGAASA

17982205

Transketolase

MLCVPLPSGASS

    R
KAA

17982141

ATP synthase F1, beta chain

MA

    K
AATP
    K
TTAAAEA

17982826

DNA-binding protein HU alpha

MPMN

    K
NELVA

17982154*

Leucine, isoleucine, valine, threonine and alanine binding protein

MGVPTM

    RK
TLFSGVALAAVIAFGGSAWA

17983192*

General L-amino acid-binding periplasmic protein AAPJ precursor

M

    KK
TLMTGVLGAAALFGIASGASA

17982682

50S ribosomal protein L11

MA

    KK
VAGQL
    K
LQVPAGA

17983290

Dihydrodipicolinate synthase

MLGVPSICF

    R
SS
    R
MLKGSITA

86283673*

Dipeptide ABC transporter, substrate binding

MMIT

    R
LS
    R
KF
    R
LLSAGAALSLLMMAAPSAFA


Putative signal peptides were predicted as described by Tjalsma et al. [47] and Pugsley [48]. *Proteins likely to be secreted via the Sec pathway. Signal peptide: the hydrophobic H-domain is in italics; positively charged amino acids are underlined; the signal peptide cleavage sites comprise the last three amino acid residues and are in bold.

Graham et al. Genome Biology 2007 8:R110   doi:10.1186/gb-2007-8-6-r110

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