Table 2 |
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|
Expression of undifferentiated and differentiated ESC markers |
|||||||||||||
|
Meta-libraries |
Embryonic stem cell libraries |
||||||||||||
|
|
|
||||||||||||
|
Markers |
CG-Meta |
CGN-Meta |
ESC-Meta |
WA01 |
WA01-M |
WA07 |
WA09 |
WA13 |
WA14 |
HSF-6 |
ES03 |
ES04 |
BG01 |
|
|
|||||||||||||
|
Undiff |
|||||||||||||
|
cx43 |
390.379 |
799.779 |
1635.9 |
1806.3 |
1182.32 |
1501.08 |
1155.02 |
1791.03 |
1720.1 |
970.938 |
2127.51 |
1486.37 |
2538.6 |
|
Oct4 |
0 |
0 |
1093.07 |
1433.46 |
1397.71 |
634.932 |
883.381 |
972.402 |
1376.08 |
432.023 |
1280.41 |
1247.4 |
1665.95 |
|
Tdgf1 |
13.9733 |
0 |
665.447 |
716.729 |
1131.92 |
767.057 |
252.394 |
339.21 |
801.146 |
329.585 |
374.871 |
578.3 |
1199.88 |
|
Sox2 |
43.6666 |
42.8454 |
406.121 |
398.183 |
265.793 |
352.332 |
675.905 |
257.8 |
518.389 |
320.677 |
350.528 |
358.451 |
416.489 |
|
Dppa4 |
11.3533 |
4.76059 |
386.637 |
463.34 |
595.745 |
572.54 |
290.895 |
303.028 |
494.826 |
231.6 |
189.87 |
430.141 |
421.447 |
|
Lefty-b |
0 |
14.2818 |
245.218 |
173.753 |
9.16532 |
77.0727 |
32.0841 |
90.456 |
348.734 |
102.438 |
73.0268 |
258.084 |
233.036 |
|
Rex-1 |
38.4266 |
14.2818 |
105.813 |
112.215 |
82.4879 |
80.7428 |
132.614 |
31.6596 |
98.965 |
40.0846 |
160.659 |
62.1314 |
158.662 |
|
Lefty-a |
0.873332 |
4.76059 |
102.454 |
54.2976 |
9.16532 |
25.6909 |
0 |
31.6596 |
70.6894 |
22.2692 |
24.3423 |
76.4694 |
168.579 |
|
Nanog |
0 |
0 |
89.6892 |
65.1572 |
77.9051 |
110.104 |
66.3071 |
135.684 |
70.6894 |
0 |
92.5006 |
195.953 |
44.6238 |
|
Nodal |
0 |
0 |
47.6999 |
21.719 |
4.58266 |
40.3714 |
6.41681 |
58.7964 |
84.8272 |
80.1692 |
48.6846 |
52.5727 |
64.4566 |
|
Foxd3 |
1.74666 |
0 |
23.1781 |
28.9587 |
45.8266 |
11.0104 |
32.0841 |
13.5684 |
9.42524 |
4.45385 |
24.3422 |
19.1174 |
49.582 |
|
Dppa2 |
0 |
0 |
14.7803 |
18.0992 |
36.6613 |
14.6805 |
4.27787 |
0 |
9.42525 |
4.45385 |
4.86845 |
14.338 |
69.4148 |
|
Lck |
0 |
0 |
13.1007 |
14.4794 |
13.748 |
18.3506 |
0 |
22.614 |
23.5631 |
4.45385 |
4.86845 |
23.8967 |
14.8746 |
|
utf-1 |
0 |
0 |
11.0852 |
10.8595 |
18.3306 |
0 |
10.6947 |
13.5684 |
0 |
17.8154 |
14.6054 |
0 |
34.7074 |
|
Tert-1 |
0 |
0 |
6.7183 |
10.8595 |
13.748 |
7.34026 |
10.6947 |
9.0456 |
4.71262 |
4.45385 |
4.86845 |
0 |
0 |
|
abcg2 |
0.873332 |
14.2818 |
2.01549 |
0 |
4.58266 |
3.67013 |
0 |
0 |
0 |
4.45385 |
4.86845 |
0 |
4.9582 |
|
dppa3 |
0 |
0 |
1.34366 |
0 |
4.58266 |
0 |
2.13894 |
0 |
0 |
4.45385 |
4.86845 |
0 |
4.9582 |
|
cx45 |
0 |
0 |
0.67183 |
0 |
4.58266 |
3.67013 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
|
Diff |
|||||||||||||
|
brachyury |
0 |
0 |
3.35915 |
0 |
0 |
0 |
0 |
40.7052 |
0 |
4.45385 |
0 |
0 |
0 |
|
afp |
0 |
0 |
8.06196 |
3.61984 |
0 |
0 |
8.55575 |
49.7508 |
4.71262 |
334.038 |
9.7369 |
4.77934 |
4.9582 |
|
krt15 |
52.3999 |
0 |
0.335915 |
0 |
4.58266 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
|
sox-1 |
8.73332 |
0 |
0.335915 |
0 |
0 |
0 |
0 |
0 |
0 |
8.90769 |
0 |
0 |
0 |
|
fgf5-1 |
48.0332 |
14.2818 |
22.1704 |
21.719 |
27.496 |
11.0104 |
10.6947 |
13.5684 |
18.8505 |
17.8154 |
19.4738 |
28.676 |
19.8328 |
|
|
|||||||||||||
|
Expression of defined ESC markers normalized to tags per million. Data for Meta ESCs (Meta-ESC), malignant (Meta-CG) and normal differentiated (Meta-CGN) cells are included for comparison. Diff, differentiated; undiff, undifferentiated. |
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|
Hirst et al. Genome Biology 2007 8:R113 doi:10.1186/gb-2007-8-6-r113 |
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