Figure 4.

Patterns and levels of nucleotide variation in ANC sequences. (a) The comparative derived allele frequency (DAF) spectrums for phase II HapMap single nucleotide polymorphisms (SNPs) in nonaccelerated conserved noncoding (CNC) sequences (n = 48,811), accelerated noncoding (ANC) sequences (n = 682), ANC sequences outside of segmental duplications, copy number variants (CNVs), retroposed genes or pseudogenes (n = 610), in the two controls (n = 28,408 and n = 28,722), in the power CNC sequences (n = 10,882), and in the 60 individuals of the Yoruban (YRI) population. (b) The comparative distributions of F_ST values for all phase II HapMap SNPs in ANC sequences (n = 688), ANC sequences outside of segmental duplications, CNVs, retroposed genes or pseudogenes (n = 620), power CNC sequences (n = 11,267), and nonaccelerated CNC sequences (n = 52,210).