Genome Biology

official impact factor 6.89

Open Access Highly Access Research

Evolutionary history and functional implications of protein domains and their combinations in eukaryotes

Masumi Itoh, Jose C Nacher, Kei-ichi Kuma, Susumu Goto and Minoru Kanehisa*

Author Affiliations

Bioinformatics Center, Institute for Chemical Research, Kyoto University, Gokasho, Uji, Kyoto 611-0011, Japan

For all author emails, please log on.

Genome Biology 2007, 8:R121 doi:10.1186/gb-2007-8-6-r121

Published: 25 June 2007

Additional files

Additional data file 1:

Provided is a figure showing detailed phylogenetic relationship among 47 eukaryotes.

Format: PDF Size: 184KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional data file 2:

This figure illustrates the difference in the number of combination partners among each group-specific domain in extant deuterostomes.

Format: PDF Size: 11KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional data file 3:

This figure illustrates the difference in the number of combination partners among each group-specific domain in extant invertebrates.

Format: PDF Size: 11KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional data file 4:

This figure illustrates the difference in the number of combination partners among each group-specific domain in extant fungi.

Format: PDF Size: 13KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional data file 5:

This figure illustrates the difference in the number of combination partners among each group-specific domain in extant protists.

Format: PDF Size: 11KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional data file 6:

This figure illustrates the difference in the number of combination partners among each group-specific domain in extant plants.

Format: PDF Size: 8KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional data file 7:

Provided are tables showing the statistics of domain assignments for eukaryotes (Supplementary Table 1) and all results of history reconstruction (Supplementary Table 2).

Format: XLS Size: 52KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data