Table 5

Effects of RNAi and cadmium on C. elegans reproduction
Target gene
 CGC gene name
 Reproduction rate (minus cadmium)*
 Reproduction rate (plus cadmium)*
 Diff. of medians
 P value†
T10B9.1
 cyp-13A4
 0.92, 0.92, 0.88, 0.96, 0.87
 0.57, 0.59, 0.61, 0.79, 0.72
 0.31
 0.008
F28D1.3
 thn-1
 1.04, 1.02, 1.14, 1.03
 0.89, 0.86, 0.92, 0.92
 0.13
 0.029
F35E8.11
 cdr-1
 1.01, 1.02, 0.94, 0.95, 1.19, 1.04
 1.38, 1.21, 0.88, 0.79, 0.80, 0.84
 0.15
 0.394
Y39B6A.24
1.10, 1.03, 1.09
 1.01, 1.21, 1.03
 0.06
 0.700
T26H2.5
0.88, 0.99, 0.81
 0.74, 0.95, 1.00
 -0.07
 1.000
K11G9.6
 mtl-1
 0.85, 1.13, 0.99, 0.90, 1.07
 0.97, 1.16, 1.12, 1.08, 1.12
 -0.13
 0.222
T27F6.2
 clec-12
 1.10, 0.90, 1.00, 1.03, 0.64, 0.90
 1.05, 1.32, 1.42, 0.94, 1.32, 0.83
 -0.24
 0.180
C17H1.4
0.87, 0.89, 1.13
 0.91, 1.06, 1.75
 -0.15
 0.686
C08E3.10
0.94, 0.93, 1.03
 1.39, 1.24, 1.26
 -0.32
 0.100
M88.1
 ugt-62
 0.93, 1.03, 0.99, 1.05, 0.98, 0.89
 1.08, 0.94, 1.34, 0.83, 0.95, 0.88
 0.04
 0.818
Y39E4A.2
 ttm-1
 0.73, 0.88, 1.05, 0.91, 0.94, 0.83, 1.01, 1.03
 0.86, 0.82, 1.12, 0.91, 0.94, 0.93, 0.83, 0.85
 0.04
 0.721
F42C5.3
1.01, 0.94, 1.02, 1.12, 1.05, 0.99
 1.06, 1.19, 1.10, 0.94, 0.91, 0.90
 0.02
 0.818
F53H2.1
1.06, 0.94, 1.00, 1.20, 0.95, 0.93
 1.27, 1.30, 1.05, 1.05, 1.07, 0.96
 -0.08
 0.132
F09B9.1
0.76, 1.04, 1.06, 0.89, 1.13, 0.96, 1.01
 1.04, 0.73, 0.95, 0.72, 0.88, 0.85, 0.92
 0.13
 0.073
Y46G5A.24
1.10, 0.94, 1.12
 0.98, 0.87, 0.80
 0.23
 0.200

*The reproduction rate was calculated by comparing the number of offspring with the targeted gene knocked-down by RNAi to those without RNAi in the same cadmium-treatment group during a two day reproduction period after nematodes reached L4 stage of development. †Wilcoxon Rank-sum tests were applied for significance tests.

Cui et al. Genome Biology 2007 8:R122   doi:10.1186/gb-2007-8-6-r122

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