Table 1

Suspicious regions in the human chromosome 1 alignment

Species
Aligned residues
Residues in suspicious regions
Suspicious regions
Residues with high phastCons score in suspicious regions

Chimp
211,636,048
(86%)
7,722
(0.004%)
103
174
(2.3%)
Rhesus
198,482,753
(80%)
32,789
(0.02%)
358
214
(0.7%)
Rabbit
87,544,213
(35%)
2,053,030
(2.3%)
24,210
24,037
(1.2%)
Mouse
92,668,918
(37%)
3,033,524
(3.3%)
36,594
25,175
(0.8%)
Rat
87,532,024
(35%)
3,141,584
(3.6%)
37,231
34,373
(1.1%)
Dog
132,538,114
(54%)
1,661,141
(1.3%)
19,277
8,383
(0.5%)
Cow
124,582,989
(50%)
1,524,553
(1.2%)
18,020
6,563
(0.4%)
Armadillo
81,991,879
(33%)
1,451,731
(1.8%)
17,306
25,172
(1.7%)
Elephant
88,888,989
(36%)
2,047,450
(2.3%)
23,089
30,143
(1.5%)
Tenrec
67,619,223
(27%)
2,495,171
(3.7%)
26,697
26,611
(1.1%)
Opossum
31,534,309
(13%)
4,657,853
(14.8%)
41,302
120,445
(2.6%)
Chicken
9,106,790
(4%)
2,363,996
(26.0%)
18,397
235,152
(9.9%)
Frog
5,916,044
(2%)
1,432,427
(24.2%)
10,947
219,613
(15.3%)
Tetraodon
5,167,534
(2%)
1,765,895
(34.2%)
9,508
240,568
(13.6%)
Fugu
4,630,234
(2%)
1,167,357
(25.2%)
8,437
169,851
(14.6%)
Zebrafish
5,855,213
(2%)
1,669,490
(28.5%)
10,963
324,159
(19.4%)
All species
219,711,964
(89%)
21,334,060
(9.7%)
185,452
1,127,826
(5.3%)

Aligned portions of the 247 Mbp of human chromosome 1 with respect to each of the other 16 vertebrates. Column 2 shows the total number of residues of human chromosome 1 that are aligned to the other species, together with its percentage of 247 Mbp, the size of human chromosome 1. Column 3 shows the total number of residues that are in suspicious regions, together with its percentage of the corresponding number in column 2. The number of suspicious regions is shown in column 4. Column 5 shows the total number of residues that are in suspicious regions and have a phastCons score greater than 0.5, together with its percentage of the corresponding number in column 3.

Prakash and Tompa Genome Biology 2007 8:R124   doi:10.1186/gb-2007-8-6-r124