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Resolution: standard / high Figure 14.
Finding true q-values. (a) Plot of the percentage of all probesets called 'differentially expressed' that are
unbound probesets at various q-value cutoffs. (b) Mean log2 intensity versus mean log2 difference between C and S replicates for all
probesets. Probesets are colored based on their classification. Empty probesets are
grey, and those that can be mapped to a transcript are colored by fold change as indicated
by the colored lines, which represent the true fold change of each classification.
(c) Same plot as (b), but probesets are colored by q-values. Green symbols represent probesets with calculated q-values below 0.10, and red symbols represent probesets with q-values < 0.0003 (observed FDR of 10%).
Schuster et al. Genome Biology 2007 8:R126 doi:10.1186/gb-2007-8-6-r126 |