Comparative analysis of transposed element insertion within human and mouse genomes reveals Alu's unique role in shaping the human transcriptome
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* Corresponding author: Gil Ast gilast@post.tau.ac.il
Genome Biology 2007, 8:R127 doi:10.1186/gb-2007-8-6-r127
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BioMed Central: 9 citations
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Research
Rajesh Pandey, Amit K Mandal, Vineet Jha, Mitali Mukerji Genome Biology 2011, 12:R117 (23 November 2011) HSF binding to conserved sites in Alu repeats initiates an antisense transcript-mediated response to heat shock
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Minireview
TEs or not TEs? That is the evolutionary question Keren Vaknin, Amir Goren, Gil Ast Journal of Biology 2009, 8:83 (23 October 2009) |
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Research article
Chiu-Jung Huang, Wan-Yi Lin, Che-Ming Chang, Kong-Bung Choo BMC Molecular Biology 2009, 10:74 (25 July 2009) |
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Research article
Retrocopy contributions to the evolution of the human genome Robert Baertsch, Mark Diekhans, W James Kent, David Haussler, Jürgen Brosius BMC Genomics 2008, 9:466 (8 October 2008) |
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Discovery notes
Noa Sela, Adi Stern, Wojciech Makalowski, Tal Pupko, Gil Ast Biology Direct 2008, 3:41 (8 October 2008) |
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Research
Exon creation and establishment in human genes André Corvelo, Eduardo Eyras Genome Biology 2008, 9:R141 (23 September 2008) A comparative genomics study of alternatively spliced exons showing that the relative local abundance of splicing regulatory motifs influences splicing decisions in humans. |
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Research article
Biased exonization of transposed elements in duplicated genes: A lesson from the TIF-IA gene Maayan Amit, Noa Sela, Hadas Keren, Ze'ev Melamed, Inna Muler, Noam Shomron, Shai Izraeli, Gil Ast BMC Molecular Biology 2007, 8:109 (29 November 2007) Exonization of transposed elements is higher within duplicated genes, implying that duplicates of the transcription initiation factor gene TIF-1A, for example, are free from the evolutionary constraints on single-copy genes.
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Software
Britta Mersch, Noa Sela, Gil Ast, Sándor Suhai, Agnes Hotz-Wagenblatt BMC Genetics 2007, 8:78 (6 November 2007) The automated pipeline SERpredict can detect predicted tissue- or tumor-specific transcript isoforms that originated due to transposable elements, which changed or created exons by inserting into the mouse and human genomes.
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Research article
Exonization of active mouse L1s: a driver of transcriptome evolution? Tomasz Zemojtel, Tobias Penzkofer, Jörg Schultz, Thomas Dandekar, Richard Badge, Martin Vingron BMC Genomics 2007, 8:392 (26 October 2007) |