Comparative analysis of transposed element insertion within human and mouse genomes reveals Alu's unique role in shaping the human transcriptome
-
* Corresponding author: Gil Ast gilast@post.tau.ac.il
1 Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv 69978, Israel
2 HUSAR Bioinformatics Lab, Department of Molecular Biophysics, German Cancer Research Center (DKFZ), Im Neuenheimer Feld, D-69120 Heidelberg, Germany
Genome Biology 2007, 8:R127 doi:10.1186/gb-2007-8-6-r127
Published: 27 June 2007Additional files
Additional data file 1:
Presented is a table describing the number of exonizations based on the existence of two ESTs/cDNA.
Format: DOC Size: 62KB Download file
This file can be viewed with: Microsoft Word Viewer
Additional data file 2:
Presented is a table of all χ2 test P values of all TE exonization levels.
Format: DOC Size: 22KB Download file
This file can be viewed with: Microsoft Word Viewer
Additional data file 3:
Presented is a table of statistical χ2 test P values for the preference of all TE exonizations in the sense/antisense orientation.
Format: DOC Size: 45KB Download file
This file can be viewed with: Microsoft Word Viewer
Additional data file 4:
Presented 4 is a table of statistical χ2 test P values for the preference of all TE exonizations in the UTR.
Format: DOC Size: 48KB Download file
This file can be viewed with: Microsoft Word Viewer
Additional data file 5:
Presented is an example of Alu exonization within a non-protein-coding gene.
Format: DOC Size: 222KB Download file
This file can be viewed with: Microsoft Word Viewer
Additional data file 6:
Presented is an illustration showing alignment of mouse L1 (Lx8) and human L1 (L1MC4).
Format: DOC Size: 54KB Download file
This file can be viewed with: Microsoft Word Viewer
Additional data file 7:
Presented is an illustration showing the populations of different families of L1 within human and mouse.
Format: DOC Size: 42KB Download file
This file can be viewed with: Microsoft Word Viewer
Additional data file 8:
Presented is a table of cDNA and EST accessions, confirming the noncanonical 3' splice site of the alternative intron within CWF19L1 gene.
Format: DOC Size: 43KB Download file
This file can be viewed with: Microsoft Word Viewer
Additional data file 9:
Presented is a table showing the domains contributed by TE exons.
Format: DOC Size: 42KB Download file
This file can be viewed with: Microsoft Word Viewer
Additional data file 10:
Presented is a table of tissue and cancer-specific TEs.
Format: DOC Size: 89KB Download file
This file can be viewed with: Microsoft Word Viewer
Additional data file 11:
Presented is a table of the potential splice sites of all TEs.
Format: DOC Size: 77KB Download file
This file can be viewed with: Microsoft Word Viewer
Additional data file 12:
Presented is an illustration showing RT-PCR of ACAD9 Alu exonization in different human cell lines.
Format: DOC Size: 184KB Download file
This file can be viewed with: Microsoft Word Viewer
Additional data file 13:
Presented is an Excel file containing coordinates of all tissue-specific and cancer specific exons in both human and mouse.
Format: XLS Size: 52KB Download file
This file can be viewed with: Microsoft Excel Viewer
