Mixture modeling of transcript abundance classes in natural populations

Wen-Ping Hsieh¹^,2 , Gisele Passador-Gurgel¹ , Eric A Stone³ and Greg Gibson¹

¹Department of Genetics, Gardner Hall, North Carolina State University, Raleigh, North Carolina 27695-7614, USA

²Department of Statistics, 825 General Building III, National Tsing Hua University, Kuang-Fu Road, Hsinchu, 30013, Taiwan

³Department of Statistics, and Bioinformatics Research Center, 1500 Partners II Building, 840 Main Campus Drive, North Carolina State University, Raleigh, North Carolina 27695, USA

author email corresponding author email

Genome Biology 2007, 8:R98doi:10.1186/gb-2007-8-6-r98


Published:	4 June 2007

Subject areas: Genome studies, Bioinformatics, Evolution

Additional files

Additional data file 1:

This document summarizes the analysis of the distribution of rare TACs among lines within each of the three experimental datasets.

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Additional data file 2:

The experimental design is illustrated. Each line is represented by four measurements: two involving control samples and two nicotine-treated samples. These were obtained from four microarrays, with a balance of Cy3 and Cy5 dyes, and a randomized loop. For example, line 2 was hybridized as control Cy3 to line 5 nicotine Cy5 on one array, and control Cy5 to line 1. Two different loops were generated, one for each population.

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