Genome Biology
Volume 8
Issue 7 |
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MinireviewA small RNA makes a Bic differenceHowell F Moffett1 and Carl D Novina1,2  1Cancer Immunology and AIDS, Dana-Farber Cancer Institute and Department of Pathology, Harvard Medical School, Boston, MA 02115, USA 2Broad Institute of Harvard and MIT, Cambridge, MA 02141, USA  author email corresponding author email
Genome Biology 2007,
8:221doi:10.1186/gb-2007-8-7-221
Subject areas: Immunology, Genetics, Biochemistry and structural biology Abstract
The first highly specific knockouts of a microRNA, miR155, in mice result in multiple defects in adaptive immunity, and also show the feasibility of investigating at least some microRNAs by gene knockout. | 
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