A C. jejuni network enriched for putative essential proteins. The network contains C. jejuni orthologs of genes proposed to be essential in E. coli (triangles), B. subtilis (diamonds), or in both organisms (rectangles). Additional proteins (circles) were included only if they interacted with more than one of the putative essential proteins. All of the protein interactions shown have confidence scores > 0.5. The map contains 264 proteins and 480 interactions. Proteins are colored based on their functional classification ; red, ribosomal protein synthesis and modification; blue, DNA replication, restriction/modification, recombination and repair; green, cell envelope; turquoise, aminoacyl tRNA synthetase and modification; orange, biosynthesis of amino acids and fatty acids; purple, energy and central intermediary metabolism; lavender, cofactor, prosthetic group and carrier biosynthesis; gray, purines, pyrimidines, nucleosides and nucleotide biosynthesis; brown, transcription and translation; yellow, hypothetical; pink, miscellaneous. Gene names can be read by zooming in.
Parrish et al. Genome Biology 2007 8:R130 doi:10.1186/gb-2007-8-7-r130