Table 2

Simulation of expected number of differentially expressed ortholog sets: ortholog overview statistics

Category
Total
Up/down

Unique Ames mouse genes
7,188
3,517/3,671
Unique Little mouse genes
7,157
3,442/3,715
Unique fly genes
10,395
4,951/5,444
Unique worm genes
12,414
5,799/6,615



Worm-fly orthologs
3,588
NA
Worm-Ames orthologs
2,469
NA
Fly-Ames orthologs
3,125
NA
Fly-Little orthologs
3,105
NA
Worm-Little orthologs
2,464
NA
Worm-fly-Little orthologs
2,152
NA
Worm-fly-Ames orthologs
2,323
NA



DE unique genes, worm
953
558/395
DE unique genes, fly
1,169
893/276
DE genes, Ames
1,416
761/655
DE genes, Little
1,042
575/467

The number of unique genes for each dataset shows the number of remaining probe sets in each analysis following removal of non-reporting probe sets, promiscuous and orphan probe sets, and multiple probe sets that report the same gene (in each case, the most significant probe set was retained). Total orthologs: number of ortholog pairs/sets with expression data in each of the relevant datasets. Differentially expressed (DE) unique genes: number of significantly differentially expressed (at q < 0.1) unique genes in each dataset.

McElwee et al. Genome Biology 2007 8:R132   doi:10.1186/gb-2007-8-7-r132

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