Table 2

Transcripts enriched in C. elegans neurons

Category
Embryonic pan-neural
Larval pan-neural
Embryonic A-class
Larval A-class

Ion channels/receptors/membrane proteins
122
156
60
41
     Acetylcholine receptors
13
24
9
9
     GABA receptors
1
4

3
     Glutamate receptors
8
8
1
2
     Potassium channels
11
24
8
10
     Calcium channels
8
10
7
4
     DEG/ENaC channels
3
10
1
1
     Stomatins
3
7
2
1
     Other ligand-gated ion channels
6
13
2
2
     Gap junction proteins (innexins)
4
4
1
1
     Symporters/exchangers/transporters
24
27
12
3
     Other membrane proteins
41
25
17
5





Axon guidance
4
8
8
3





Adhesion/Ig domain
6
17
10
11





Cytoskeleton-related
33
34
16
5





Transcriptional control
90
91
38
10
     Homeobox
8
28
3
3
     Hormone receptors
24
15
5
1
     Aryl-hydrocarbon receptors
1
3
1

     SMADs

3
1
1
     HMG box
5
5


     HLH factors
2
4
1
1
     Other transcription factors
32
25
13
4
     General factors
18
8
14






Kinase/phosphatase
82
79
51
18





GPCR signaling
107
169
42
25
     G-protein coupled receptors
85
137
33
18
     G-proteins
8
10
3
3
     Regulators of G-protein signaling (GTPases, GEFs, GRKs)
7
8
4
2
     Adenylate/guanylate cyclases
7
14
2
2





Rab/Rho/Rac GTPase signaling
17
7
7
2





Neuropeptides
39
58
11
13
     FMRFamide-like (flp)
13
20
4
5
     Neuropeptide-like (nlp)
13
18
3
4
     Insulin-like
9
11
2
1
     TGF-beta
1
3
1
1
     Pro-protein convertases
3
6
1
3





Calcium binding
18
26
12
9





Synaptic vesicle associated
38
53
25
17





RNA binding
22
14
22
3





Ubiquitin associated
39
19
12
3





Enzymes
199
103
111
30





Collagens
2
1
5
24





Other
297
205
174
44





Unnamed/uncharacterized
159
127
161
56





Unclassified
363
395
230
98





Total
1,637
1,562
995
412

Von Stetina et al. Genome Biology 2007 8:R135   doi:10.1186/gb-2007-8-7-r135