Table 2

Transcripts enriched in C. elegans neurons

Category

Embryonic pan-neural

Larval pan-neural

Embryonic A-class

Larval A-class

Ion channels/receptors/membrane proteins

122

156

60

41

Acetylcholine receptors

13

24

9

9

GABA receptors

1

4

3

Glutamate receptors

8

8

1

2

Potassium channels

11

24

8

10

Calcium channels

8

10

7

4

DEG/ENaC channels

3

10

1

1

Stomatins

3

7

2

1

Other ligand-gated ion channels

6

13

2

2

Gap junction proteins (innexins)

4

4

1

1

Symporters/exchangers/transporters

24

27

12

3

Other membrane proteins

41

25

17

5

Axon guidance

4

8

8

3

Adhesion/Ig domain

6

17

10

11

Cytoskeleton-related

33

34

16

5

Transcriptional control

90

91

38

10

Homeobox

8

28

3

3

Hormone receptors

24

15

5

1

Aryl-hydrocarbon receptors

1

3

1

SMADs

3

1

1

HMG box

5

5

HLH factors

2

4

1

1

Other transcription factors

32

25

13

4

General factors

18

8

14

Kinase/phosphatase

82

79

51

18

GPCR signaling

107

169

42

25

G-protein coupled receptors

85

137

33

18

G-proteins

8

10

3

3

Regulators of G-protein signaling (GTPases, GEFs, GRKs)

7

8

4

2

Adenylate/guanylate cyclases

7

14

2

2

Rab/Rho/Rac GTPase signaling

17

7

7

2

Neuropeptides

39

58

11

13

FMRFamide-like (flp)

13

20

4

5

Neuropeptide-like (nlp)

13

18

3

4

Insulin-like

9

11

2

1

TGF-beta

1

3

1

1

Pro-protein convertases

3

6

1

3

Calcium binding

18

26

12

9

Synaptic vesicle associated

38

53

25

17

RNA binding

22

14

22

3

Ubiquitin associated

39

19

12

3

Enzymes

199

103

111

30

Collagens

2

1

5

24

Other

297

205

174

44

Unnamed/uncharacterized

159

127

161

56

Unclassified

363

395

230

98

Total

1,637

1,562

995

412

Von Stetina et al. Genome Biology 2007 8:R135   doi:10.1186/gb-2007-8-7-r135