Table 1

Sequence divergence versus tissue expression breadth

No. of tissues
N (total = 3,893)
dSM
Kp
Ka
Ks
Ka/Ks

01-10
986
0.688
0.337
0.107
0.733
0.150


0.735
0.328
0.084
0.673
0.119


0.221
0.110
0.093
0.299
0.122
11-50
1,889
0.701
0.333
0.079
0.708
0.116


0.752
0.328
0.058
0.633
0.089


0.216
0.093
0.073
0.307
0.103
51-55
1,018
0.732
0.328
0.050
0.639
0.079


0.791
0.323
0.031
0.572
0.054


0.208
0.079
0.057
0.305
0.085

p value (K-W test)
<10-5
0.226
<10-75
<10-18
<10-62

N, number of genes; dSM, promoter divergence (see text); Kp, promoter substitution rate; Ka, non-synonymous substitution rate; Ks, synonymous substitution rate. Mean (top), median (middle), and standard deviation (bottom) are indicated for each variable. Numbers in bold indicate significant differences at p < 0.001 in each expression group with respect to the rest (two-sample Wilcoxon-Mann-Whitney test). The last row shows the p value of Kruskal-Wallis (K-W) test that evaluates differences between the three tissue expression breadth groups.

Farré et al. Genome Biology 2007 8:R140   doi:10.1186/gb-2007-8-7-r140

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