Table 3 |
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|
Transcription factors with predicted binding motifs over-represented in HK gene promoters |
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|
Transcription factor |
Description |
Expression breadth |
|
|
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|
AHR and ARNT |
Aryl hydrocarbon receptor; it can interact with ARNT (AHR:ARNT heterodimer) |
INT |
|
ATF family |
Activating transcription factor |
HK |
|
CREB family |
cAMP responsive element binding protein |
INT |
|
E2F family |
E2F transcription factor |
INT and HK |
|
HIF1A |
Hypoxia inducible factor 1, alpha subunit; as AHR, it can interact with ARNT |
HK |
|
MYC and MAX |
Proto-oncogene protein c-myc and MYC associated factor X; they can form MYC:MAX heterodimers |
INT and HK |
|
NRF1 and NRF2 |
Nuclear respiratory factor 1 and 2 |
INT and HK |
|
SP1 |
SP1 transcription factor |
HK |
|
USF |
Upstream transcription factor (USF1 and USF2) |
INT |
|
|
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|
HK, housekeeping; INT, intermediate. |
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|
Farré et al. Genome Biology 2007 8:R140 doi:10.1186/gb-2007-8-7-r140 |
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