Table 3

Transcription factors with predicted binding motifs over-represented in HK gene promoters

Transcription factor

Description

Expression breadth


AHR and ARNT

Aryl hydrocarbon receptor; it can interact with ARNT (AHR:ARNT heterodimer)

INT

ATF family

Activating transcription factor

HK

CREB family

cAMP responsive element binding protein

INT

E2F family

E2F transcription factor

INT and HK

HIF1A

Hypoxia inducible factor 1, alpha subunit; as AHR, it can interact with ARNT

HK

MYC and MAX

Proto-oncogene protein c-myc and MYC associated factor X; they can form MYC:MAX heterodimers

INT and HK

NRF1 and NRF2

Nuclear respiratory factor 1 and 2

INT and HK

SP1

SP1 transcription factor

HK

USF

Upstream transcription factor (USF1 and USF2)

INT


HK, housekeeping; INT, intermediate.

Farré et al. Genome Biology 2007 8:R140   doi:10.1186/gb-2007-8-7-r140

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