siRNA screen of the human signaling proteome identifies the PtdIns(3,4,5)P3-mTOR signaling pathway as a primary regulator of transferrin uptake

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siRNA screen of the human signaling proteome identifies the PtdIns(3,4,5)P₃-mTOR signaling pathway as a primary regulator of transferrin uptake

Thierry Galvez^*, Mary N Teruel, Won D Heo, Joshua T Jones, Man L Kim, Jen Liou, Jason W Myers and Tobias Meyer^*

* Corresponding authors: Thierry Galvez galvez@mpi-cbg.de - Tobias Meyer tobias1@stanford.edu

Genome Biology 2007, 8:R142 doi:10.1186/gb-2007-8-7-r142