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Co-localization of CENP-C and CENP-H to discontinuous domains of CENP-A chromatin at human neocentromeres

Alicia Alonso1 email, Björn Fritz2,3 email, Dan Hasson1 email, György Abrusan1 email, Fanny Cheung1 email, Kinya Yoda4 email, Bernhard Radlwimmer5 email, Andreas G Ladurner2 email and Peter E Warburton1 email

1Department of Genetics and Genomic Sciences, Mount Sinai School of Medicine, 1425 Madison Avenue, New York, New York 10029, USA

2Gene Expression Unit, Meyerhofstrasse, European Molecular Biology Laboratory (EMBL), 69117 Heidelberg, Germany

3Abbott Germany, Max-Planck-Ring, 65205 Wiesbaden, Germany

4Bioscience and Biotechnology Center, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8601, Japan

5Deutsches Krebsforschungszentrum (DKFZ), Im Neuenheimer Feld, 69120 Heidelberg, Germany

author email corresponding author email

Genome Biology 2007, 8:R148doi:10.1186/gb-2007-8-7-r148

Published: 25 July 2007

Subject areas: Molecular biology, Cell biology, Genome studies


Additional files

Additional File 1:

Sliding window analysis of LINE1 density at neocentromeres.

Format: PDF Size: 252KB Download file

This file can be viewed with: Adobe Acrobat Reader

Additional File 2:

Analysis of the A+T content at neocentromeres.

Format: PDF Size: 559KB Download file

This file can be viewed with: Adobe Acrobat Reader

Additional File 3:

Thirty-four qRT-PCR primer pairs (Figure 3).

Format: DOC Size: 76KB Download file

This file can be viewed with: Microsoft Word Viewer


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