Table 2 |
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|
GFCS evaluated from species-specific ProtSemNet |
||||
| KEGG pathway |
GFCSe |
P |
GFCSd |
P |
|
|
||||
| Apoptosis (hsa04210) |
86 |
9.35 × e-8 |
5.36 |
1.59 × e-8 |
| Glycolysis (hsa00010) |
68 |
1.62 × e-10 |
7.29 |
0.84a |
| Focal adhesion (hsa04510) |
174 |
1.56 × e-14 |
12.48 |
7.51 × e-5 |
| JAK-STAT (hsa04630) |
147 |
2.52 × e-27 |
12.11 |
1.56 × e-05 |
| ATP synthesis (mmu00190) |
33 |
3.01 × e-08 |
3.42 |
1.17 × e-04 |
| Calcium signaling (mmu04020) |
102 |
0.04 |
9.24 |
2.91 × e-6 |
| Actin regulation (mmu04810) |
122 |
3.37 × e-5 |
7.47 |
6.48 × e-13 |
| Cytokine receptor (mmu04060) |
176 |
1.65 × e-39 |
15.62 |
0.99a |
| Purine metabolism (sce00230) |
111 |
3.69 × e-4 |
8.33 |
0.34a |
| MAPK (sce04010) |
78 |
5.65 × e-8 |
3.15 |
5.61 × e-8 |
| Ribosome (sce03010) |
113 |
1.61 × e-26 |
16.58 |
0.999a |
| Oxidative phosphorylation (sce00190) |
74 |
1.6 × e-12 |
5.42 |
0.001 |
|
|
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|
GFCS, group functional coherence score; JAK, Janus kinase; KEGG, Kyoto Encyclopedia of Genes and Genomes; MAPK, mitogen-activated protein kinase; ProtSemNet, protein semantic network; STAT, signal transducer and activator of transcription. aNon-significant P value. |
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|
Zheng and Lu Genome Biology 2007 8:R153 doi:10.1186/gb-2007-8-7-r153 |
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