Table 3 |
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|
GCFS evaluated from the orthologous ProtSemNet |
||||
| Protein pathway |
GFCSe |
P |
GFCSd |
P |
|
|
||||
| Apoptosis (hsa04210) |
72 |
2.54 × e-10 |
0.77 |
3.12 × e-9 |
| Glycolysis (hsa00010) |
54 |
0.0062 |
0.83 |
4.50 × e-4 |
| Focal adhesion (hsa04510) |
99 |
1.66 × e-7 |
0.58 |
1.34 × e-14 |
| JAK-STAT (hsa04630) |
153 |
2.19 × e-07 |
3.11 |
7.48 × e-11 |
| ATP synthesis (mmu00190) |
71 |
2.14 × e-4 |
0.83 |
4.28 × e-07 |
| Calcium signaling (mmu04020) |
76 |
4.43 × e-8 |
0.40 |
1.16 × e-12 |
| Actin regulation (mmu04810) |
80 |
0.0089 |
0.53 |
7.45 × e-9 |
| Cytokine receptor (mmu04060) |
199 |
2.63 × e-8 |
4.51 |
4.44 × e-12 |
| Purine metabolism (sce00230) |
130 |
2.07 × e-4 |
2.57 |
6.92 × e-19 |
| MAPK (sce04010) |
101 |
0.0069 |
1.76 |
1.76 × e-05 |
| Ribosome (sce03010) |
102 |
9.50 × e-25 |
7.19 |
0.471a |
| Oxidative phosphorylation (sce00190) |
92 |
1.41 × e-6 |
2.87 |
0 |
|
|
||||
|
GFCS, group functional coherence score; JAK, Janus kinase; MAPK, mitogen-activated protein kinase; ProtSemNet, protein semantic network; STAT, signal transducer and activator of transcription. aNon-significant P value. |
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|
Zheng and Lu Genome Biology 2007 8:R153 doi:10.1186/gb-2007-8-7-r153 |
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