Additional data file 3.

Hierarchical clustering over 186 ER- breast cancers and 813 negative kurtosis profile genes selected using the PAK algorithm, as explained in the text. Five main clusters were identified and characterized in terms of over-expression of genes related to cell cycle (CC), immune response (IR), extracellular matrix (ECM), and steroid hormone response (SR) functions. Red denotes relative over-expression and green relative under-expression.

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Teschendorff et al. Genome Biology 2007 8:R157   doi:10.1186/gb-2007-8-8-r157