Table 2

Distribution of ER- samples among clusters, prognostic groups and intrinsic subtypes

Cluster

n

Outcome

LI

ER-

Good

Poor

High

Low

Luminal B

Luminal A

Normal

Basal

HER2


CC+/IR+

39

25

14

7

2

0

0

0

38

1

CC+

37

18

17

3

5

0

0

1

33

3

ECM+

45

26

18

1

14

0

9

9

22

5

SR+

36

16

20

2

4

1

1

0

2

32

IR+

29

23

6

6

6

0

4

2

9

14


For the five clusters of Figure 2a, we give the number of samples per cluster (n) and their distributions over good/poor outcome, high/low lymphocytic infiltration (LI) score, and intrinsic subtypes as determined by the single sample predictor (SSP) classifier. Clusters were labeled by the main Gene Ontology of genes over-expressed in the group: CC+ (cell cycle), CC+/IR+ (cell cycle and immune response), ECM+ (extracellular matrix), SR+ (steroid hormone response), and IR+ (immune response). ER, estrogen receptor.

Teschendorff et al. Genome Biology 2007 8:R157   doi:10.1186/gb-2007-8-8-r157

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