Exon expression profiling reveals stimulus-mediated exon use in neural cells
-
* Corresponding authors: Alexander S Brodsky alex_brodsky@brown.edu - Pamela A Silver pamela_silver@hms.harvard.edu
1 Department of Systems Biology, 200 Longwood Avenue, Harvard Medical School, Boston, Massachusetts 02115, USA.
2 Department of Physics, Institute for Brain and Neural Systems, 182 Hope Street, Brown University, Providence, Rhode Island 02912, USA.
3 Center for Computational Molecular Biology, 115 Waterman Street, Brown University, Providence, Rhode Island 02912, USA.
4 Department of Applied Mathematics, 182 George Street, Brown University, Rhode Island 02912, USA.
5 Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, 44 Binney Street, Boston, Massachusetts 02115, USA.
6 Department of Biostatistics, Harvard School of Public Health, 655 Huntington Avenue, Boston, Massachusetts 02115, USA.
7 Department of Medicine, 200 Longwood Avenue, Harvard Medical School, Boston, Massachusetts 02115, USA.
8 Department of Medical Oncology, Dana-Farber Cancer Institute, 44 Binney Street, Boston, Massachusetts 02115, USA.
9 Department of Molecular Biology, Cell Biology, and Biochemistry, 185 Meeting Street, Brown University, Providence, Rhode Island 02903, USA.
10 Center for Genomics & Proteomics, Center for Computational Molecular Biology, 70 Ship Street, Brown University, Providence, Rhode Island 02903, USA.
Genome Biology 2007, 8:R159 doi:10.1186/gb-2007-8-8-r159
Published: 2 August 2007Additional files
Additional data file 1:
Presented is a figure of PCR data confirming the stimulus-induced transcription of known mRNAs.
Format: PDF Size: 265KB Download file
This file can be viewed with: Adobe Acrobat Reader
Additional data file 2:
Presented is a table containing the transcripts affected by elevated [Ca2+]i.
Format: TXT Size: 2.3MB Download file
Additional data file 3:
Presented is a table containing the exons affected by elevated [Ca2+]i.
Format: ZIP Size: 6.8MB Download file
Additional data file 4:
Presented is a figure presenting the distribution of the number of exons called as changing in the KCl datasets.
Format: PDF Size: 249KB Download file
This file can be viewed with: Adobe Acrobat Reader
Additional data file 5:
Presented is a table listing the GO categories enriched among transcripts affected by elevated [Ca2+]i.
Format: PDF Size: 23KB Download file
This file can be viewed with: Adobe Acrobat Reader
Additional data file 6:
Presented is a figure showing analyses of transcript and exon PCR validation.
Format: PDF Size: 405KB Download file
This file can be viewed with: Adobe Acrobat Reader
Additional data file 7:
Presented is a figure showing quantification of transcript PCR validation.
Format: PDF Size: 273KB Download file
This file can be viewed with: Adobe Acrobat Reader
Additional data file 8:
Presented is a table listing the GO categories enriched among transcripts affected at the exon level by elevated [Ca2+]i through KCl treatment.
Format: PDF Size: 33KB Download file
This file can be viewed with: Adobe Acrobat Reader
Additional data file 9:
Presented is a figure showing examples of splice form diversity identified from array data and verified by PCR.
Format: PDF Size: 310KB Download file
This file can be viewed with: Adobe Acrobat Reader
Additional data file 10:
Presented is a table of PCR primers used in this study.
Format: XLS Size: 57KB Download file
This file can be viewed with: Microsoft Excel Viewer
