  ResearchExon expression profiling reveals stimulus-mediated exon use in neural cellsAdrienne E McKee1 1Department of Systems Biology, 200 Longwood Avenue, Harvard Medical School, Boston, Massachusetts 02115, USA. 2Department of Physics, Institute for Brain and Neural Systems, 182 Hope Street, Brown University, Providence, Rhode Island 02912, USA. 3Center for Computational Molecular Biology, 115 Waterman Street, Brown University, Providence, Rhode Island 02912, USA. 4Department of Applied Mathematics, 182 George Street, Brown University, Rhode Island 02912, USA. 5Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, 44 Binney Street, Boston, Massachusetts 02115, USA. 6Department of Biostatistics, Harvard School of Public Health, 655 Huntington Avenue, Boston, Massachusetts 02115, USA. 7Department of Medicine, 200 Longwood Avenue, Harvard Medical School, Boston, Massachusetts 02115, USA. 8Department of Medical Oncology, Dana-Farber Cancer Institute, 44 Binney Street, Boston, Massachusetts 02115, USA. 9Department of Molecular Biology, Cell Biology, and Biochemistry, 185 Meeting Street, Brown University, Providence, Rhode Island 02903, USA. 10Center for Genomics & Proteomics, Center for Computational Molecular Biology, 70 Ship Street, Brown University, Providence, Rhode Island 02903, USA.
Genome Biology 2007, 8:R159doi:10.1186/gb-2007-8-8-r159
Subject areas: Molecular biology, Bioinformatics, Genome studies, Neurobiology Additional filesAdditional data file 1: Presented is a figure of PCR data confirming the stimulus-induced transcription of known mRNAs. Format: PDF Size: 265KB Download file This file can be viewed with: Adobe Acrobat Reader Additional data file 2: Presented is a table containing the transcripts affected by elevated [Ca2+]i. Format: TXT Size: 2.3MB Download file Additional data file 3: Presented is a table containing the exons affected by elevated [Ca2+]i. Format: ZIP Size: 6.9MB Download file Additional data file 4: Presented is a figure presenting the distribution of the number of exons called as changing in the KCl datasets. Format: PDF Size: 249KB Download file This file can be viewed with: Adobe Acrobat Reader Additional data file 5: Presented is a table listing the GO categories enriched among transcripts affected by elevated [Ca2+]i. Format: PDF Size: 23KB Download file This file can be viewed with: Adobe Acrobat Reader Additional data file 6: Presented is a figure showing analyses of transcript and exon PCR validation. Format: PDF Size: 405KB Download file This file can be viewed with: Adobe Acrobat Reader Additional data file 7: Presented is a figure showing quantification of transcript PCR validation. Format: PDF Size: 273KB Download file This file can be viewed with: Adobe Acrobat Reader Additional data file 8: Presented is a table listing the GO categories enriched among transcripts affected at the exon level by elevated [Ca2+]i through KCl treatment. Format: PDF Size: 33KB Download file This file can be viewed with: Adobe Acrobat Reader Additional data file 9: Presented is a figure showing examples of splice form diversity identified from array data and verified by PCR. Format: PDF Size: 310KB Download file This file can be viewed with: Adobe Acrobat Reader Additional data file 10: Presented is a table of PCR primers used in this study. Format: XLS Size: 57KB Download file This file can be viewed with: Microsoft Excel Viewer |
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