Table 2

Distribution of exons exhibiting alternative splice site choice in RefSeq transcripts and in the Exon datasets

Exon position

Type of alternative splice choice

Percentage in RefSeq database

Percentage in KCl exon

P value

Percentage in TPG exon

P value

Initial

5'

24.32

28.14

1.367 × e^-03*

27.70

8.081 × e^-05*

Initial

Alternative start

25.25

27.18

6.386 × e^-02*

30.07

6.674 × e^-08*

Internal

5'

5.31

8.02

1.179 × e^-13*

6.53

4.935 × e^-11*

Internal

3'

5.32

8.05

8.393 × e^-14*

6.77

9.659 × e^-15*

Final

Alternative termination

23.43

25.63

1.574 × e^-02*

28.55

1.110 × e^-16*

Final

3'

22.92

23.27

3.515 × e^-01

24.83

7.685 × e^-04*

RefSeq exons were classified as exhibiting 5' or 3' alternative splice site choice according their presence in RefSeq transcripts. Constituents of the potassium chloride (KCl) and thapsigargin (TPG) exon datasets were mapped to these definitions. *P values showing statistical significance for enrichment of alternative splice site choice exons at initial, internal, and final positions through a binomial test.

McKee et al. Genome Biology 2007 8:R159   doi:10.1186/gb-2007-8-8-r159