Genome Biology

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Network motif analysis of a multi-mode genetic-interaction network

R James Taylor1,2, Andrew F Siegel3 and Timothy Galitski1*

Author Affiliations

1 Institute for Systems Biology, N. 34th Street, Seattle, WA 98103 USA

2 University of British Columbia, Department of Genetics, Vancouver, BC, V6T 1Z4, Canada

3 University of Washington, Departments of Management Science, Finance, and Statistics, Seattle, WA, 98195, USA

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Genome Biology 2007, 8:R160 doi:10.1186/gb-2007-8-8-r160

Published: 2 August 2007

Additional files

Additional data file 1:

Full collection of 3n-motifs.

Format: PDF Size: 126KB Download file

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Additional data file 2:

Network pattern structure, significance, and number of instances of each 3node network pattern found in the genetic network.

Format: XML Size: 262KB Download file

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Additional data file 3:

Random distribution, parametric fit, and significance of the top 100 significant 3-node network patterns found in the genetic network.

Format: PDF Size: 8.1MB Download file

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Additional data file 4:

Full collection of 4n-motifs.

Format: PDF Size: 1.2MB Download file

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Additional data file 5:

Network pattern structure, significance, and number of instances of each 4-node network pattern found in the genetic network.

Format: XML Size: 966KB Download file

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Additional data file 6:

Random distribution, parametric fit, and significance of the top 100 significant 4-node network patterns found in the genetic network.

Format: PDF Size: 8MB Download file

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Additional data file 7:

Full collection of 2nGO-motifs.

Format: PDF Size: 23KB Download file

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Additional data file 8:

Network pattern structure, significance, and number of instances of each 2nGO network pattern found in the genetic network.

Format: XML Size: 271KB Download file

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Additional data file 9:

Random distribution, parametric fit, and significance of the top 100 significant 2nGO network patterns found in the genetic network.

Format: PDF Size: 7.7MB Download file

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Additional data file 10:

Full collection of 3nGO-motifs.

Format: PDF Size: 113KB Download file

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Additional data file 11:

Network pattern structure, significance, and number of instances of each 3nGO network pattern found in the genetic network.

Format: XML Size: 6.5MB Download file

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Additional data file 12:

Network pattern structure, significance, and number of instances of each 3nGO network pattern found in the genetic network.

Format: XML Size: 6MB Download file

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Additional data file 13:

Description of the genetic perturbations used to construct the genetic interaction network.

Format: XML Size: 1.3MB Download file

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Additional data file 14:

Cytoscape attribute file containing the genetic inequality relationships for all edges of the genetic interaction network.

Format: INEQUALITIES Size: 84KB Download file

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Additional data file 15:

Cytoscape network file of the genetic interaction network

Format: SIF Size: 50KB Download file

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Additional data file 16:

Cytoscape network file containing a subset of the full genetic interaction network.

Format: SIF Size: 5KB Download file

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Additional data file 17:

Cytoscape attribute file containing GOSlim molecular function attributes.

Format: GOSFUNCTION Size: 2KB Download file

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Additional data file 18:

NetworkMotifFinder Cytoscape plugin file.

Format: JAR Size: 772KB Download file

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Additional data file 19:

Software tutorial for the NetworkMotifFinder plugin.

Format: DOC Size: 292KB Download file

This file can be viewed with: Microsoft Word Viewer

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Additional data file 20:

Random distribution, parametric fit, and significance of the top 200 significant 3nGO network patterns found in the genetic network.

Format: PDF Size: 8MB Download file

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Additional data file 21:

Random distribution, parametric fit, and significance of the top 200 significant 3nGO network patterns found in the genetic network.

Format: PDF Size: 7.8MB Download file

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Additional data file 22:

Supplemental Figure 1: definition of the genetic interactions used in this study.

Format: PDF Size: 237KB Download file

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Additional data file 23:

Supplemental Figure 2a,b: further examples of 3n-motif subnetworks.

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Additional data file 24:

Supplemental Figure 2c,d: further examples of 3n-motif subnetworks.

Format: PDF Size: 728KB Download file

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Additional data file 25:

Supplemental Figure 2e: further examples of 4n-motif subnetworks.

Format: PDF Size: 1004KB Download file

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