Table 2

Gene Ontology categories overrepresented among the 165 genes targeted by more than 30 miRNAs

Category

Term

Count

%

P value

Biological Process 5

Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism

51

30.91

5.55E-12

Biological Process 4

Homophilic cell adhesion

15

9.09

1.82E-11

Biological Process 5

Transcription

51

30.91

1.96E-11

Biological Process 4

Regulation of cellular metabolism

54

32.73

9.26E-11

Biological Process 3

Nervous system development

23

13.94

1.49E-10

Biological Process 3

Regulation of metabolism

54

32.73

1.71E-10

Biological Process 3

Regulation of cellular physiological process

61

36.97

2.46E-09

Biological Process 3

Cell-cell adhesion

15

9.09

1.10E-08

Biological Process 4

Nucleobase, nucleoside, nucleotide and nucleic acid metabolism

56

33.94

5.15E-06

Cellular Component 3

Nucleus

72

43.64

1.31E-08

Cellular Component 3

Intracellular membrane-bound organelle

79

47.88

2.91E-04

Molecular Function 3

DNA binding

49

29.70

1.12E-08

Molecular Function 4

Transcription factor activity

30

18.18

8.45E-08

Molecular Function 3

Metal ion binding

64

38.79

1.87E-07

Molecular Function 3

Cation binding

60

36.36

6.06E-07

Molecular Function 5

Zinc ion binding

35

21.21

6.33E-05

Molecular Function 4

Calcium ion binding

23

13.94

6.74E-05

Molecular Function 4

Sequence-specific DNA binding

14

8.48

4.49E-04

Molecular Function 5

Transcription corepressor activity

6

3.64

1.12E-03

Molecular Function 3

Transcription corepressor activity

6

3.64

1.69E-03

Molecular Function 5

Calcium-transporting atpase activity

3

1.82

6.05E-03

Significant terms (P < 0.01) from levels 3-5 of each ontology are shown.

Hon and Zhang Genome Biology 2007 8:R166   doi:10.1186/gb-2007-8-8-r166