Table 2 |
|||||
|
Functional tests of candidate genes |
|||||
|
Line |
Gene |
Mean locomotor reactivity (± SE) |
F1,112 |
P value |
Human ortholog |
|
|
|||||
|
BG01127 |
muscleblind |
21.63 ± 1.47 |
37.47 |
< 0.0001 |
MBLN1 |
|
BG01259 |
Ken and barbie |
23.43 ± 1.32 |
17.26 |
< 0.0001 |
N/A |
|
BG01697 |
CG33523 |
24.13 ± 1.30 |
22.08 |
< 0.0001 |
N/A |
|
BG01761 |
Amphiphysin |
26.80 ± 0.93 |
5.66 |
0.019 |
AMPH |
|
BG01863 |
Cysteine string protein |
20.50 ± 1.54 |
46.97 |
< 0.0001 |
DNAJC5B |
|
BG02106 |
CG31145 |
26.40 ± 0.97 |
2.03 |
0.157 |
FAM20A |
|
BG02109 |
tartan |
26.15 ± 0.92 |
1.16 |
0.096 |
N/A |
|
BG02121 |
center divider |
26.80 ± 0.77 |
1.16 |
0.285 |
N/A |
|
BG02676 |
CG10990 |
25.30 ± 1.20 |
16.86 |
< 0.0001 |
PDCD4 |
|
BG02715 |
nebbish |
25.25 ± 1.27 |
14.41 |
< 0.0001 |
KIF14 |
|
|
|||||
|
The mean locomotor reactivity of the Canton S B control strain is 28.50 ± 0.20 s. Bonferroni significance threshold = 0.005. Human orthologs have homology scores of > 0.93 and Bootstrap scores of > 93%. N/A, not applicable; SE, standard error. |
|||||
|
Jordan et al. Genome Biology 2007 8:R172 doi:10.1186/gb-2007-8-8-r172 |
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