Table 2

Functional tests of candidate genes

Line

Gene

Mean locomotor reactivity (± SE)

F1,112

P value

Human ortholog


BG01127

muscleblind

21.63 ± 1.47

37.47

< 0.0001

MBLN1

BG01259

Ken and barbie

23.43 ± 1.32

17.26

< 0.0001

N/A

BG01697

CG33523

24.13 ± 1.30

22.08

< 0.0001

N/A

BG01761

Amphiphysin

26.80 ± 0.93

5.66

0.019

AMPH

BG01863

Cysteine string protein

20.50 ± 1.54

46.97

< 0.0001

DNAJC5B

BG02106

CG31145

26.40 ± 0.97

2.03

0.157

FAM20A

BG02109

tartan

26.15 ± 0.92

1.16

0.096

N/A

BG02121

center divider

26.80 ± 0.77

1.16

0.285

N/A

BG02676

CG10990

25.30 ± 1.20

16.86

< 0.0001

PDCD4

BG02715

nebbish

25.25 ± 1.27

14.41

< 0.0001

KIF14


The mean locomotor reactivity of the Canton S B control strain is 28.50 ± 0.20 s. Bonferroni significance threshold = 0.005. Human orthologs have homology scores of > 0.93 and Bootstrap scores of > 93%. N/A, not applicable; SE, standard error.

Jordan et al. Genome Biology 2007 8:R172   doi:10.1186/gb-2007-8-8-r172

Open Data