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MicroRNAs show a wide diversity of expression profiles in the developing and mature central nervous system

Marika Kapsimali123, Wigard P Kloosterman4, Ewart de Bruijn4, Frederic Rosa5, Ronald HA Plasterk4* and Stephen W Wilson1*

Author Affiliations

1 Department of Anatomy and Developmental Biology, UCL, Gower Street, London WC1E 6BT, UK

2 DEPSN, UPR2197, CNRS, avenue de la Terrasse, 91198, Gif-sur-Yvette, France

3 Génétique Moléculaire du Développement, INSERM U784, Ecole Normale Supérieure, 46, rue d'Ulm, 75230 Paris, France

4 Hubrecht Laboratory, Centre for Biomedical Genetics, Uppsalalaan 8, 3584 CT Utrecht, the Netherlands

5 Génétique Moléculaire du Développement, INSERM U784, Ecole Normale Supérieure, 46, rue d'Ulm, 75230 Paris, France

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Genome Biology 2007, 8:R173  doi:10.1186/gb-2007-8-8-r173

Published: 21 August 2007

Additional files

Additional data file 1:

miR-7 expression in the zebrafish brain.

Format: EPS Size: 9.7MB Download file

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Additional data file 2:

miR-9 expression in the 3 days post-fertilization (dpf) zebrafish brain.

Format: EPS Size: 4.2MB Download file

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Additional data file 3:

miR-9 expression in the 5 days post-fertilization (dpf) zebrafish brain.

Format: EPS Size: 2.9MB Download file

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Additional data file 4:

miR-9 expression in the adult zebrafish brain.

Format: EPS Size: 4.1MB Download file

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Additional data file 5:

miR-34 expression in the zebrafish brain.

Format: EPS Size: 4MB Download file

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Additional data file 6:

miR-92b expression in the zebrafish brain.

Format: EPS Size: 3.7MB Download file

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Additional data file 7:

miR-124 expression in the zebrafish brain.

Format: EPS Size: 3.1MB Download file

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Additional data file 8:

miR-128 expression in the zebrafish brain.

Format: EPS Size: 4MB Download file

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Additional data file 9:

miR-135c expression in the zebrafish brain.

Format: EPS Size: 3.4MB Download file

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Additional data file 10:

miR-137 expression in the zebrafish brain.

Format: EPS Size: 4.2MB Download file

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Additional data file 11:

miR-138 expression in the zebrafish brain.

Format: EPS Size: 2.8MB Download file

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Additional data file 12:

miR-153a expression in the zebrafish brain.

Format: EPS Size: 4.1MB Download file

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Additional data file 13:

miR-181a expression in the zebrafish brain.

Format: EPS Size: 2.9MB Download file

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Additional data file 14:

miR-181b expression in the zebrafish brain.

Format: EPS Size: 8.5MB Download file

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Additional data file 15:

miR-183 expression in the zebrafish brain.

Format: EPS Size: 7.5MB Download file

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Additional data file 16:

miR-200a expression in the zebrafish brain.

Format: EPS Size: 4MB Download file

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Additional data file 17:

miR-218a expression in the zebrafish brain.

Format: EPS Size: 3.8MB Download file

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Additional data file 18:

miR-219 expression in the zebrafish brain.

Format: EPS Size: 4MB Download file

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Additional data file 19:

miR-221 expression in the zebrafish brain.

Format: EPS Size: 3.9MB Download file

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Additional data file 20:

miR-222 expression in the zebrafish brain.

Format: EPS Size: 3.5MB Download file

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Additional data file 21:

miR-375 expression in the zebrafish brain.

Format: EPS Size: 2.4MB Download file

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Additional data file 22:

let-7a expression in the zebrafish brain.

Format: EPS Size: 2.3MB Download file

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Additional data file 23:

let-7b expression in the zebrafish brain.

Format: EPS Size: 3MB Download file

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Additional data file 24:

let-7c expression in the zebrafish brain.

Format: EPS Size: 3MB Download file

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Additional data file 25:

Expression of other miRNAs in the zebrafish brain.

Format: EPS Size: 3.8MB Download file

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Additional data file 26:

Legends of the figures presented in Additional data files 1-25 and 29 and the list of neuroanatomical abbreviations.

Format: DOC Size: 183KB Download file

This file can be viewed with: Microsoft Word Viewer

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Additional data file 27:

Tables A-I providing detailed information about the expression of each miRNA in different structures of the zebrafish central and/or peripheral nervous system.

Format: DOC Size: 1.1MB Download file

This file can be viewed with: Microsoft Word Viewer

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Additional data file 28:

Tables J-L, listing the miRNAs analyzed, the family/cluster they belong to and the mismatch locked nucleic acid (LNA) probe sequences used to test specificity of corresponding fully matching LNA probes.

Format: DOC Size: 52KB Download file

This file can be viewed with: Microsoft Word Viewer

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Additional data file 29:

Mismatch test for let-7a, miR-92b, miR-153a and miR-181a.

Format: EPS Size: 7.6MB Download file

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