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MicroRNAs show a wide diversity of expression profiles in the developing and mature central nervous system

Marika Kapsimali* 1,2,3 email, Wigard P Kloosterman* 4 email, Ewart de Bruijn4 email, Frederic Rosa5 email, Ronald HA Plasterk4 email and Stephen W Wilson1 email

1Department of Anatomy and Developmental Biology, UCL, Gower Street, London WC1E 6BT, UK

2DEPSN, UPR2197, CNRS, avenue de la Terrasse, 91198, Gif-sur-Yvette, France

3Génétique Moléculaire du Développement, INSERM U784, Ecole Normale Supérieure, 46, rue d'Ulm, 75230 Paris, France

4Hubrecht Laboratory, Centre for Biomedical Genetics, Uppsalalaan 8, 3584 CT Utrecht, the Netherlands

5Génétique Moléculaire du Développement, INSERM U784, Ecole Normale Supérieure, 46, rue d'Ulm, 75230 Paris, France

author email corresponding author email* Contributed equally

Genome Biology 2007, 8:R173doi:10.1186/gb-2007-8-8-r173

Published: 21 August 2007

Subject areas: Molecular biology, Development, Genetics


Additional files

Additional data file 1:

miR-7 expression in the zebrafish brain.

Format: EPS Size: 9.9MB Download file

Additional data file 2:

miR-9 expression in the 3 days post-fertilization (dpf) zebrafish brain.

Format: EPS Size: 4.3MB Download file

Additional data file 3:

miR-9 expression in the 5 days post-fertilization (dpf) zebrafish brain.

Format: EPS Size: 3MB Download file

Additional data file 4:

miR-9 expression in the adult zebrafish brain.

Format: EPS Size: 4.2MB Download file

Additional data file 5:

miR-34 expression in the zebrafish brain.

Format: EPS Size: 4.1MB Download file

Additional data file 6:

miR-92b expression in the zebrafish brain.

Format: EPS Size: 3.8MB Download file

Additional data file 7:

miR-124 expression in the zebrafish brain.

Format: EPS Size: 3.2MB Download file

Additional data file 8:

miR-128 expression in the zebrafish brain.

Format: EPS Size: 4.1MB Download file

Additional data file 9:

miR-135c expression in the zebrafish brain.

Format: EPS Size: 3.5MB Download file

Additional data file 10:

miR-137 expression in the zebrafish brain.

Format: EPS Size: 4.3MB Download file

Additional data file 11:

miR-138 expression in the zebrafish brain.

Format: EPS Size: 2.9MB Download file

Additional data file 12:

miR-153a expression in the zebrafish brain.

Format: EPS Size: 4.2MB Download file

Additional data file 13:

miR-181a expression in the zebrafish brain.

Format: EPS Size: 3MB Download file

Additional data file 14:

miR-181b expression in the zebrafish brain.

Format: EPS Size: 8.7MB Download file

Additional data file 15:

miR-183 expression in the zebrafish brain.

Format: EPS Size: 7.6MB Download file

Additional data file 16:

miR-200a expression in the zebrafish brain.

Format: EPS Size: 4.1MB Download file

Additional data file 17:

miR-218a expression in the zebrafish brain.

Format: EPS Size: 3.8MB Download file

Additional data file 18:

miR-219 expression in the zebrafish brain.

Format: EPS Size: 4.1MB Download file

Additional data file 19:

miR-221 expression in the zebrafish brain.

Format: EPS Size: 4MB Download file

Additional data file 20:

miR-222 expression in the zebrafish brain.

Format: EPS Size: 3.6MB Download file

Additional data file 21:

miR-375 expression in the zebrafish brain.

Format: EPS Size: 2.5MB Download file

Additional data file 22:

let-7a expression in the zebrafish brain.

Format: EPS Size: 2.3MB Download file

Additional data file 23:

let-7b expression in the zebrafish brain.

Format: EPS Size: 3.1MB Download file

Additional data file 24:

let-7c expression in the zebrafish brain.

Format: EPS Size: 3.1MB Download file

Additional data file 25:

Expression of other miRNAs in the zebrafish brain.

Format: EPS Size: 3.9MB Download file

Additional data file 26:

Legends of the figures presented in Additional data files 1-25 and 29 and the list of neuroanatomical abbreviations.

Format: DOC Size: 183KB Download file

This file can be viewed with: Microsoft Word Viewer

Additional data file 27:

Tables A-I providing detailed information about the expression of each miRNA in different structures of the zebrafish central and/or peripheral nervous system.

Format: DOC Size: 1.1MB Download file

This file can be viewed with: Microsoft Word Viewer

Additional data file 28:

Tables J-L, listing the miRNAs analyzed, the family/cluster they belong to and the mismatch locked nucleic acid (LNA) probe sequences used to test specificity of corresponding fully matching LNA probes.

Format: DOC Size: 52KB Download file

This file can be viewed with: Microsoft Word Viewer

Additional data file 29:

Mismatch test for let-7a, miR-92b, miR-153a and miR-181a.

Format: EPS Size: 7.8MB Download file


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