Figure 2.

Cytokine gene expression. (a) A list of all cytokines and chemokines (as defined by Gene Ontology annotation) was used to extract gene expression data. Genes with at least a 2.5-fold change from baseline in at least three arrays are displayed. (b) Transcript levels of cytokine mRNA in peripheral blood mononuclear cells and ELISAs for detection of soluble cytokines in the serum. IL, interleukin; MCP, monocyte chemoattractant protein; MIP, macrophage inflammatory protein; TNF, tumor necrosis factor.