Table 2

Sixteen total gene functional groups identified by the Functional Classification Tool

Gene functional group no.

Associated biology

Group enrichment score


1

Chemokine/cytokine

3.37

2

Transcription regulation

2.89

3

Signal transduction/membrane receptors

2.68

4

Kinase activity

2.54

5

DNA damage/repair

2.23

6

Iron binding

2.05

7

RNA processing/splicing factors

1.81

8

Organic acid transport

1.71

9

Cation/ion transport

1.69

10

DNA metabolism/chromosome organization

1.53

11

Cellular macromolecule catabolism

1.41

12

Metalloprotease

1.34

13

Macrotubule

1.24

14

Protein localization/fusion

1.17

15

Amine metabolism

1.1

16

RAS small GTPase

1.03


The genes of demo list 2 were analyzed by the Functional Classification Tool. The major biology terms associated with each group are manually summarized based on gene-term enrichment buttons provided for each functional group.

Huang et al. Genome Biology 2007 8:R183   doi:10.1186/gb-2007-8-9-r183

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