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Functional annotations enriched among genes upregulated* in BMP2+ cells compared to control cells in seven-day-old EBs and undifferentiated BMP2 ES cells |
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| Category |
Term |
Count |
p value |
|
|
|||
| GOTERM_MF_5 |
Zinc ion binding |
46 |
5.6E-5 |
| GOTERM_CC_5 |
Nucleus |
95 |
3.3E-4 |
| GOTERM_BP_5 |
Cellular protein metabolism |
66 |
3.3E-4 |
| GOTERM_BP_5 |
Protein catabolism |
10 |
4.9E-3 |
| GOTERM_BP_5 |
Apoptosis |
17 |
5.9E-3 |
| GOTERM_BP_5 |
Biopolymer modification |
38 |
6.0E-3 |
| GOTERM_BP_5 |
Biopolymer catabolism |
10 |
6.9E-3 |
| GOTERM_BP_5 |
Positive regulation of programmed cell death |
8 |
9.1E-3 |
| GOTERM_MF_5 |
ATP binding |
30 |
1.4E-2 |
| GOTERM_BP_5 |
Response to unfolded protein |
5 |
1.5E-2 |
| GOTERM_BP_5 |
Transcription |
47 |
1.5E-2 |
| GOTERM_BP_5 |
Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism |
45 |
2.7E-2 |
| GOTERM_BP_5 |
Regulation of programmed cell death |
11 |
3.8E-2 |
| GOTERM_BP_5 |
Regulation of progression through cell cycle |
11 |
5.1E-2 |
| GOTERM_BP_5 |
Protein kinase cascade |
8 |
5.3E-2 |
| GOTERM_BP_5 |
Regulation of protein kinase activity |
5 |
5.6E-2 |
| GOTERM_BP_5 |
Small GTPase mediated signal transduction |
9 |
5.6E-2 |
| GOTERM_BP_5 |
Post replication repair |
2 |
6.2E-2 |
| GOTERM_MF_5 |
Ubiquitin-protein ligase activity |
8 |
6.2E-2 |
| GOTERM_BP_5 |
Regulation of apoptosis |
10 |
7.4E-2 |
| GOTERM_BP_5 |
Protein transport |
16 |
7.5E-2 |
| GOTERM_MF_5 |
Protein kinase activity |
15 |
8.3E-2 |
| KEGG_REACTION |
Phytoceramide+h2o<=>fattyacid+phytosphingosine |
3 |
8.7E-2 |
| GOTERM_CC_5 |
Lytic vacuole |
6 |
8.8E-2 |
| KEGG_PATHWAY |
MAPK signaling pathway |
9 |
9.5E-2 |
|
*Change fold >2, Student's t-test p value < 0.01. Count indicates the number of genes in the functional annotation category. The p value is from gene enrichment in annotation terms calculated by the Fisher's exact t-test. | |||
Doss et al. Genome Biology 2007 8:R184 doi:10.1186/gb-2007-8-9-r184 |
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