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Coverage and error models of protein-protein interaction data by directed graph analysis

Tony Chiang1,2*, Denise Scholtens3, Deepayan Sarkar2, Robert Gentleman2 and Wolfgang Huber1

1 EMBL, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, UK

2 Fred Hutchinson Cancer Research Center, Computational Biology Group, Fairview Avenue North, Seattle, WA 98109-1024, USA

3 Northwestern University, Department of Preventive Medicine, N Lake Shore Drive, Chicago, IL 60611-4402, USA

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Genome Biology 2007, 8:R186 doi:10.1186/gb-2007-8-9-r186

Published: 10 September 2007

Additional files

Additional data file 1:

Provided is a document demonstrating a full end-to-end analysis of the protein interaction datasets.

Format: GZ Size: 1.3MB Download file

Open Data

Additional data file 2:

Presented is the Bioconductor package ppiStats (version 1.3.5 of 22 June 2007) in 'source' format. ppiStats contains the novel methods developed in this paper.

Format: GZ Size: 5.1MB Download file

Open Data

Additional data file 3:

Presented is the Bioconductor package ppiStats in 'Windows binary' format.

Format: ZIP Size: 515KB Download file

Open Data