Table 1

Across experiment comparison of protein subsets associated with systematic error

Not in Krogan et al. [11]

In Krogan et al. [11]

Not in Gavin et al. [10]

624

63

In Gavin et al. [10]

31

12

P = 6.5 × 10^-4

Odds ratio = 3.82

This table compares the proteins affected by a reciprocity artifact from the datasets of Gavin and coworkers [10] and Krogan and colleagues [11]. Binomial tests were applied to identify the affected protein sets within each experiment, and their overlap was assessed in the 2 × 2 contingency table. In this table, the binomial tests were applied to the two experimental datasets independently, and only those proteins in which the in-degree is much larger than the out-degree are considered. Shown P value and odds ratio were calculated from the 2 × 2 table using the hypergeometric distribution.

Chiang et al. Genome Biology 2007 8:R186   doi:10.1186/gb-2007-8-9-r186