Table 3

Across experiment comparison of protein subsets associated with systematic error

Not in Krogan et al. [11]

In Krogan et al. [11]


Not in Gavin et al. [10]

651

45

In Gavin et al. [10]

26

8

P = 1.8 × 10-3

Odds ratio = 4.44


This table represents the comparison of proteins affected by a reciprocity artifact from the datasets of Gavin and coworkers [10] and Krogan and colleagues [11] as well. Before conducting the binomial test, the data graphs were restricted to the nodes common to the viable bait/prey (VBP) sets of both experiments. Again, only those proteins identified by the binomial test in which in-degree is much larger than the out-degree is compared. Both the P value and odds ratio, obtained using the hypergeometric distribution, show a strong association between the two sets of proteins.

Chiang et al. Genome Biology 2007 8:R186   doi:10.1186/gb-2007-8-9-r186

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