Table 3 |
||||||
|
Transcription factor-binding motifs in promoters of loneliness-related genes |
||||||
|
TFBM |
Low lonely |
High lonely |
Ratio |
t |
df |
p |
|
|
||||||
|
V$CEBP_Q2 (C/EBP) |
0.714 |
0.340 |
0.476 |
-2.76 |
120.3 |
0.0067 |
|
V$OCT1_03 (Oct) |
1.400 |
0.793 |
0.566 |
-2.60 |
115.7 |
0.0106 |
|
V$CREL_01 (NF-κB) |
0.129 |
0.377 |
2.935 |
2.62 |
74.6 |
0.0108 |
|
V$GATA1_03 (GATA) |
0.557 |
0.245 |
0.440 |
-2.52 |
120.2 |
0.0131 |
|
V$OCT1_04 (Oct) |
0.086 |
0.000 |
0.000 |
-2.54 |
69.0 |
0.0132 |
|
V$OCT_C (Oct) |
0.071 |
0.000 |
0.000 |
-2.30 |
69.0 |
0.0242 |
|
V$AHRARNT_01 (AHR) |
0.043 |
0.208 |
4.843 |
2.28 |
65.4 |
0.0258 |
|
V$BARBIE_01 (BARBIE) |
0.043 |
0.208 |
4.843 |
2.28 |
65.4 |
0.0258 |
|
V$GR_Q6 (GRE) |
0.257 |
0.094 |
0.367 |
-2.17 |
112.1 |
0.0325 |
|
V$STAT_01 (STAT) |
0.014 |
0.151 |
10.566 |
2.13 |
57.4 |
0.0376 |
|
V$TAL1BETAE47_01 |
0.057 |
0.000 |
0.000 |
-2.04 |
69.0 |
0.0447 |
|
V$TAL1ALPHAE47_01 |
0.057 |
0.000 |
0.000 |
-2.04 |
69.0 |
0.0447 |
|
V$IRF1_01 (IRF1) |
0.086 |
0.000 |
0.000 |
-1.93 |
69.0 |
0.0572 |
|
|
||||||
|
TFBM: transcription factor-binding motif (V$ = TRANSFAC Vertebrate). Low lonely: average TFBM prevalence in promoters of genes up-regulated in low-lonely. High lonely: average TFBM prevalence in promoters of genes up-regulated in high-lonely. Ratio: high-lonely/low-lonely. t Statistic: Welch formula for unequal variances. df: continuous degrees of freedom for Welch unequal variance t-test. p value: two-tailed. |
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|
Cole et al. Genome Biology 2007 8:R189 doi:10.1186/gb-2007-8-9-r189 |
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